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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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Iterative Querying in Web-Based Database Application
Published 2002“…Web applications are increasingly relying on databases. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Ripple effect in web applications
Published 2010“…The number of internet web applications is rapidly increasing in a variety of fields and not much work has been done for ensuring their quality, especially after modification. …”
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A Framework for Multi-cloud Cooperation with Hardware Reconfiguration Support
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
Published 2020“…HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. …”
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Towards context-adaptable Web service policies
Published 2011“…These policies can then be statically woven into compositeWeb services (e.g. a BPEL process). The synergy between context, policies and aspects allows to increase the level of adaptability of Web services at different levels of applications.…”
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Web service discovery: Rationale, challenges, and solution directions
Published 2024“…Web Service technology paved the way for microservice architecture as it is a feature of modern web applications that resulted from the rise of SOA. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…For extension (%) at peak load, a decreasing trend was found vs. stretch rate (R2 = 0.81; two-tailed p value = 0.037) where increasing the displacement rate from 1 mm/min to 500 mm/min corresponds to a 22% decrease in the relative elongation of the mesh. …”
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Computing ripple effect for web applications. (c2007)
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On the sampling and integration rates of process noise
Published 1995“…In this paper we consider a class of process noise in navigation, and study the effects of sampling and integration rates on the covariance of the respective sampled and integrated signals. …”
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Using XML-based multicasting to improve web service scalability
Published 2012“…A major WS feature is SOAP, a simple, robust and extensible XML-based protocol for the exchange of messages. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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A comprehensive design and rating study of evaporative coolers and condensers. Part I. Performance evaluation
Published 2020“…Abstract The mathematical models of evaporative fluid coolers and evaporative condensers are studied in detail to perform a comprehensive design and rating analysis. The mathematical models are validated using experimental as well as numerical data reported in the literature. …”
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Release of colloids in saturated porous media under transient hydro-chemical conditions: A pore-scale study
Published 2021“…Favorable, medium-favorable and unfavorable colloids (i.e., repulsion absent, repulsion at long-range of separation distances and attraction absent with the micromodel surface, respectively) were deposited in the micromodel and then a series of colloid release experiments were conducted at different conditions including increasing the flow rate, decreasing the ionic strength and increasing the solution pH. …”