Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…”

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…The upregulation of 40S ribosomal protein S9 (3-fold), 40S ribosomal protein S15 (4.2-fold), 40S ribosomal protein S18 (2.5-fold), and 60S ribosomal protein L22 (4.4-fold) implied the induction of translation machinery. …”

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma Younes (6424865)

“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”

Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers by Mostafa Shibl (18810412)

“…LSTM provided the best results with an accuracy of 95% for predicting the most appropriate power rating (PR) for EVCS, followed by RF, DT, DNN, SVM, KNN, and NB. Additionally, LSTM was also the model with the smallest error rate, at a value of ±0.7%, followed by RF, DT, KNN, SVM, DNN, and NB. …”

Vocal Changes in Patients With Polycystic Ovary Syndrome by Hannoun, Antoine

“…In the control group, one subject had vocal fold edema and one subject had vocal fold nodules. …”
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Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet by Bassil, Maya

“…Results The intake of S. libanotica extract was associated with a significant decrease in fasting serum glucose (102.9 ± 10.8 in GII and 87.5 ± 6.4 in GIII vs. 152.1 ± 7.9 mg/dl in controls) and a two fold increase in fasting serum insulin (GIII) and liver glycogen content (GII and GIII). …”
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Hygienic quality of chlorinated city water stored in household tanks in Byblos, Lebanon. (c2004) by Abi Chedid, Najib

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Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…Those of South Asian descent had a 13-fold increased risk of having elevated glycated haemoglobin levels, and Filipinos a 4.5-fold increase, compared to the native Arab population. …”

Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions by Vryzas, Zisis

“…The yield stress increased linearly with temperature by almost three-fold, the flow consistency index decreased exponentially with temperature by almost five-fold and the flow behavior index increased by about 20%, tending towards the Newtonian value. …”
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…The absence of LAT2 led to increased intramuscular glutamine (Gln) accumulation (6.3‐fold, <i>p</i> < 0.0001), accompanied by a reduction in skeletal muscle proteolysis during fasting (0.61‐fold, <i>p</i> = 0.0004) primarily due to decreased proteasomal and autophagic activity (0.45‐fold, <i>p</i> = 0.016 and 0.7‐fold, <i>p</i> = 0.002, respectively). …”

Zirconium phytate-based proton conductors for high-temperature fuel cell applications by Nimir, Wessam Ahmed Mohamed

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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines by Ismail, Jana

“…Thus, according to Drug Reduction Index (DRI), a combination of 6-fold less concentration of cisplatin with 1.3-fold less concentration of CBD yields a 95% cell growth inhibition. …”
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis by Milane, Aline

“…Consistent with this, P-gp function was also increased by 1.5-fold and riluzole brain disposition was decreased by 1.7-fold in mSOD1 mice. …”
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Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine by Debendra Muduli (20748758)

“…The effectiveness has been evaluated using two standard datasets called G1020 and ORIGA with the $$10 \times 5$$-fold stratified cross-validation technique to ensure reliable evaluation. …”

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis by Charbel Abi Khalil (14150028)

“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”

Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients by Bouquet, Antoine

“…The main limitation of this strategy is that it can be offered only in selected patients with synchronous disease,5, 6, 7, 8, 9 and 10 and it is associated with an increased risk of postoperative complications when major liver resection is combined with resection of the primary tumor.11, 12 and 13 Recently, a “reverse strategy,” in which preoperative chemotherapy is followed by resection of the CLM and then by resection of the colorectal primary at a second operation, has been proposed for patients with advanced synchronous CLM, and in particular, for patients in whom the primary is located in the rectum.14 The rationale for the reverse strategy is 2-fold: primary-related complications (such as bleeding, obstruction, or perforation) are rare in patients with stage IV colorectal cancer receiving combination chemotherapy15 and 16 and treatment of the metastatic disease is not delayed by local therapy for the primary tumor (surgery, and in the case of rectal cancer, radiotherapy or radiochemotherapy) or by complications of surgical treatment of the primary tumor. …”
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Processing Effects on the Oxytetracycline and Tylosin Antibiotic Residues in Middle Eastern Dairy Products by Saidy, Liz

“…Curding step had a significant (p=0.028) effect on OTC only with the concentration increasing by almost 1.5 folds. Acidification and heating of whey to produce Double Cream decreased significantly (p=0.037) OTC concentration by 14.7 to 46.3%, while TYL concentration increased significantly (p=0.000) by 300%. …”
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