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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
Published 2024“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
Published 2023“…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…”
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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact
Published 2020“…The results showed a decrease in the MSE of V<sub>mp</sub> by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I<sub>mp</sub> by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …”
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained?
Published 2025“…Fasting blood glucose decreased significantly across the five time points, from 9.27 ± 4.11preop to 7.06 ± 2.70 <sub>year9 </sub>mmol/L. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
Published 2025“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”
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Flexural Response of Reinforced Concrete One-Way Slabs Embedded with Pet Bottles
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Characterizing the dynamics of climate and native desert plants in Qatar
Published 2024“…However, the probability of rainfall events over 80 mm was less than 5%, while low rainfall seasons (1–17 mm) were more likely (90–99% chance). …”
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Effect of Construction Void Defects on Flexural and Axial Load Capacity of Reinforced Concrete Members
Published 2018Get full text
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Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis
Published 2020“…Glucagon-like peptide (GLP-1) agonist therapy was associated with a significant decrease in Hb<sub>A1c</sub> (%) (SMD -0.68) and a non-significant decrease in weight (kg) (SMD -2.57) and systolic blood pressure (SBP) (mmHg) (SMD -3.50) after Ramadan. …”
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Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
Published 2019“…Treatment with a combination of 2DG (5 mM) and metformin (2 mM) also significantly decreased cell proliferation, migration and tubulogenic capacity when compared to cells that were treated with either 2DG or metformin alone. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…Statistically significant findings suggest an increasing trend for Prolene® stiffness vs. stretch rate (R2 = 0.9679; two-tailed p value = 0.0025) where the stiffness increases 26.2% when increasing the displacement rate from 1 to 500 mm/min. For extension (%) at peak load, a decreasing trend was found vs. stretch rate (R2 = 0.81; two-tailed p value = 0.037) where increasing the displacement rate from 1 mm/min to 500 mm/min corresponds to a 22% decrease in the relative elongation of the mesh. …”
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Evapotranspiration and water availability response to climate change in the Middle East and North Africa
Published 2021“…Outcomes reveal that the MENA region is indeed vulnerable to a surge in temperature, which can increase evapotranspiration losses and decrease water availability. Under the shared socioeconomic pathway (SSP2-4.5), the potential evapotranspiration (PET) has been projected to increase throughout the MENA region by up to 0.37 mm per year during the middle of the twenty-first century (2021–2050) and by up to 0.51 mm per year during the end of the twenty-first century (2071–2100). …”
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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…These scenarios were in this order: Overhang Louvers in three dimensions 1200mm, 1500mm and 1800mm, 90 Vertical Fins, 45 Vertical fins as scenario two, Egg-crate, Horizontal Louvers, Vertical Louvers and a double skin façade in scenario six. …”
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Simultaneous Bilateral Neck of Femur Fracture in a Young Adult with Underlying Metabolic Disturbances
Published 2020“…The patient was treated with three 6.5 mm cannulated cancellous screws on one side and a sliding hip screw on the other side and was followed with strict physical therapy and rehabilitation plan. 6 months from the injury, a radiographic bilateral union achieved with the patient back to his normal daily activity and noncontact sports. …”
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Particle size impact on pyrolysis of multi-biomass: a solid-state reaction modeling study
Published 2023“…Both activation energy and pre-exponential factor decreased from 18.78 to 5.57 kJ/mol and 1.16 E+10 to 1.48 E+08 with reducing particle sizes. …”