Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…We then used the modified cell lines to quantify the alteration in chemo sensitivity of those cells to treatment with DNA Damaging Agents (DDAs) such as Cisplatin and Epirubicin or DNA Damage Response (DDRs) drugs like Olaparib. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection by Asfia Sultana (19170880)

“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> by Safa Salim (9186786)

“…One such gene is the single-stranded DNA-binding protein 3 (<i>SSBP3</i>) and its Drosophila melanogaster ortholog is called sequence-specific single-stranded DNA-binding protein (<i>Ssdp</i>). …”

A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact by Samer Gowid (15955152)

“…The results showed a decrease in the MSE of V_mp by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I_mp by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …”

Effect of Hypoxia on Maximal Fat Oxidation Rate During Incremental Cycling : Relationship to the Gas Exchange Threshold by Youmna Elsayed Hassanein (21547490)

“…The aim of this study was to evaluate MFO in normoxia (NORM) and hypoxia (HYPO) during exercise at intensities matched relative to the respiratory compensation point (RCP).</p><h3>Methods</h3><p dir="ltr">Seventeen recreationally active adults (5 females/12 males; age: 36.2 ± 7.4 year; body mass: 76.6 ± 13.1 kg) performed a ramp and a step incremental test, in NORM (The fraction of inspired oxygen; FiO₂ ≈ 21%) and HYPO (FiO₂ ≈ 13.5%), on separate days. …”

Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? by Wahiba Elhag (5245547)

“…Fasting blood glucose decreased significantly across the five time points, from 9.27 ± 4.11preop to 7.06 ± 2.70 _year9mmol/L. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance by Mohammed Hamidat (3722086)

“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity by Mohamed Abu-Farha (18535590)

BRET-Based Biosensors for Nucleic Acid Detection and Impact of Molecular Crowding Monitoring by Asfia Sultana (19170880)

“…Our work extended to designing BioNADs targeting SARS-CoV-2 variants by conjugating specific, fluorescently modified molecular beacons to NLuc-functionalized DNA for viral nucleic acid detection. …”

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis by Charbel Abi Khalil (14150028)

“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”

High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry by E. Safamariyam (22330186)

“…Furthermore, the repeatability of the Ce_0.6 -MoS₂ sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…”

Optimization of design and operation of solar assisted district cooling systems by Dana M. Alghool (18387132)

“…Moreover, the existence of the cold-water TES in the system depends on the chosen chiller capacity and the cooling demand of the case study. …”

Characterizing the dynamics of climate and native desert plants in Qatar by Meshal Abdullah (17746950)

“…However, the probability of rainfall events over 80 mm was less than 5%, while low rainfall seasons (1–17 mm) were more likely (90–99% chance). …”

Hydrothermal and irreversibility numerical analysis of helical coil energy storage tank with nano-encapsulated PCMs: A comprehensive study with magnetic filled, Soret/Dufour, and m... by Mohammed Azeez Alomari (20482592)

“…On the other hand, average values of Nusselt and Sherwood are decreased with the rise of the Hartmann number. Furthermore, Nusselt average and Sherwood’s average decrease by 21.4 % and 24.9 % respectively when Darcy’s number increases from 0.1 to 10^-4.…”

Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 by Sarah Naja (9954737)

“…</p><h3>Limitations</h3><p dir="ltr">There is no recognized optimal cut-off point to distinguish ‘high risk’ in pregnancy-related anxiety scales.…”

Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity by Dania Nazeeh Ibrahim (21547487)

“…</p><h3>Methods</h3><p dir="ltr">Seventeen healthy active adults, male and female, with a background in cycling, completed a ramp and step incremental exercise testing in normoxia (NORM; FiO₂≈21%) and hypoxia (HYPO; FiO₂≈13.5%) on four occasions. Both ramp tests determined the respiratory compensation point (RCP) and gas exchange threshold (GET). …”

Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs by Albertus Retnanto (17269237)

“…Additionally, the transit time showed a 26–42% range decrease in the travel period, indicating that the cement was stronger under increased pressure and temperature. …”

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Doua Abdelrahman (17280667)

“…Results: Only 1.4% (70/5026) of the samples had detectible B19V DNA in their blood. B19V DNA prevalence statistically decreased with age (p = 0.03). …”