Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S., El-Shoukrofy

“…The two most effective 15-LOX inhibitors, 2a and 2b, exhibited 69 % and 57 % of quercetin's action, respectively. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review by Sunji, Nadine

“…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). Close to 90 % of all positive diagnoses were among MSM. …”
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) by Connor, Izumi

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Non-linear relationship between real commodity price volatility and real effective exchange rate: The case of commodity-exporting countries by Boubakri, Salem

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Production of flexible nanocomposite membranes for x-ray detectors by Ahmad I., Ayesh

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Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy, Mallah

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Electric vehicles charging management using deep reinforcement learning considering vehicle-to-grid operation and battery degradation by Mostafa M., Shibl

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Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan by Hiroaki, Nishiuchi

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Human health risks associated with the consumption of groundwater in the Gaza Strip by Basem, Shomar

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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane by Vasavi, Boggarapu

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Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan, Sirin

“…OBSI test results at various pavements with different mean texture depths of dense-graded pavement showed that the temperature coefficient varied from 0.052 dB/°C to 0.142 dB/°C. There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials by Pieter Francsois, Fouche

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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

“…FindingsGlobal DALYs increased from 2·63 billion (95% UI 2·44–2·85) in 2010 to 2·88 billion (2·64–3·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14·2% (95% UI 10·7–17·3) between 2010 and 2019. …”
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Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021 by Nicholas, Steel

“…Exposure to these major risk factors differed by country, with trends of increasing exposure to high BMI and decreasing exposure to tobacco smoke observed in all countries during 1990–2021. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

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Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 by Yingzhao, Jin

“…Across five age groups, the rates of prevalence, YLDs, and DALYs for RA, NP, LBP, gout, and OMSKDs sharply increased from ages 15–19 to 35–39; however, these were negligible for OA before age 30 but increased notably at ages 30–34, rising at least 6-fold by 35–39. …”
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
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