Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. by Seidel, Monika

“…The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. …”
Get full text
Get full text

Dynamic workload patterns prediction for proactive auto-scaling of web applications by Iqbal W.

“…The framework is implemented and experimentally evaluated using historical access logs of three real web applications, each with increasing, decreasing, periodic, and randomly varying arrival rate behaviors. …”
Get full text
Get full text

Decreased soil moisture due to warming drives phylogenetic diversity and community transitions in the tundra by Scharn, Ruud

Get full text
Get full text
Get full text

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
Get full text
Get full text
Get full text

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
Get full text
Get full text
Get full text

Acute and chronic toxicity assessments of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) on the calanoid copepod Acartia clausi: Effects on survival, development, sex-ratio and... by Emna, Djebbi

“…The most resistant life stage was N1 with LC50 values > 1500 μg L-1 and >5000 μg L-1, respectively for E2 and EE2. …”
Get full text
Get full text
Get full text

Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract by Ahmed, Rashid

“…The DPPH assay demonstrated a higher antioxidant potential (IC-50 value of 133 μg/ml), which was comparable to the IC-50 of ascorbic acid (122.4 μg/ml). …”
Get full text
Get full text

Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model by Zakaria, Zain Z

“…Our data showed that AuNRs caused mortality with a calculated LC50 of EC50,24hpf of AuNRs being 9.1 μg/mL, while a higher concentration of AuNRs was revealed to elicit developmental abnormalities. …”
Get full text
Get full text

Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
Get full text
Get full text

Evaluation of Apoptotic, Antiproliferative, and Antimigratory Activity of Origanum syriacum against Metastatic Colon Cancer Cells by Aldisi S.S.

“…OSEE showed a concentration-dependent apoptotic and antiproliferative effect on LoVo and SW620 cells at 500 μg mL−1 or higher after 48 h of exposure. Additionally, OSEE inhibited the migration of both LoVo and SW620 cells by decreasing (50–75%) wound-healing capacity at 500 and 1,000 μg mL−1. …”
Get full text
Get full text

In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy by AlanaziR.

“…Results In both term-pregnant and non-pregnant uterine strips, H 2 O 2 elicited a biphasic response, consisting of a transient contraction followed by a persistent decrease in spontaneously generated contractions, contractions induced by oxytocin, and contractions induced by high Ca +2 (all P< 0.01, compared with controls) in a concentration-dependent manner. …”
Get full text
Get full text

Selection of Bacillus spp. with decontamination potential on multiple Fusarium mycotoxins by Zahoor Ul, Hassan

“…Complete degradation (100%) of ZEN was observed at a contamination level of 0.375 μg/ml in LB, while showing a decreasing trend of degradation (87 and 84%) at increasing levels of mycotoxins (0.750 and 1.50 μg/ml LB medium, respectively). …”
Get full text
Get full text
Get full text

Possible Ionic Effects of NaCl on Two Mexican Wheat Cultivars by Yasseen, B.T. [بسام طه ياسين]

“…The ionic agents, NaCl and Na2SO+, decreased K* and Ca2* in the leaves, while PEG had little effect on leaf iontent of r* ana- Ca2i lif in.r. ug"",t increased phosphorus in leaves of both cultivars, but PEG had the smallest effect. …”
Get full text

The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis by Jamialahmadi, Tannaz

“…This meta-analysis aimed to provide an answer as to whether statins do affect decreasing the plasma levels of atherogenic TMAO. Methods A systematic literature search in PubMed, Scopus, Embase, and Web of Science was performed from inception to January 1st, 2023. …”
Get full text
Get full text

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Da'as, Sahar I.

“…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …”
Get full text
Get full text
Get full text

Osteoporosis in patients with stroke: A cross-sectional study by Tomasevic-Todorovic, Snezana

Get full text
Get full text

Global patterns and predictions of seafloor biomass using random forests by Wei, C.-L.

“…Lowest values are consistently encountered on the central abyssal plains of major ocean basins The shift of biomass dominance groups with depth is shown to be affected by the decrease in average body size rather than abundance, presumably due to decrease in quantity and quality of food supply. …”
Get full text
Get full text

Effects of supervisor’s personality on the support, abuse, and feedback provided to junior accountants by Saadullah, Shahriar M.

“…Methodology/approach – We conducted a web-based study with 115 accountants from a top 100 US accounting firm. …”
Get full text
Get full text
Get full text

A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department by Losier, Mia

“…Where identified, benefits of AMS interventions primarily included improvement in delivery of care or a decrease in antimicrobial utilization; however, most studies were rated as having unclear or high risk of bias. …”
Get full text
Get full text

INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS by Abayomi, Oyebamiji Abib

“…Microplastics pose greater threats as they can be mistaken for food by filter-feeders and planktivorous fish, and can also adsorb large quantities of recalcitrant organic pollutants (OPs) which biomagnify up the marine food web, hence, explains the need for their investigation. …”
Get full text