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Decreased phosphodiesterase activities in cardiac hypertrophy
Published 2007“…The whole cell patch-clamp technique was used to record the associated CNG current (ICNG) and ICa,L. Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Stem Cells International<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1155/2019/3041262" target="_blank">https://dx.doi.org/10.1155/2019/3041262</a></p>…”
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Potential of horizontal louvers in increased energy savings in a commercial building in Dubai
Published 2018“…The dissertation creates a benchmark for horizontal louver configuration and its role in increasing the energy savings. …”
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Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains
Published 2017“…No homogenization of the transformation strain field was observed as a result of either stress increase or thermal cycling. …”
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A 28 nm CMOS 10 bit 100 MS/s Asynchronous SAR ADC with Low-Power Switching Procedure and Timing-Protection Scheme
Published 2021“…The proposed ADC is fabricated in a 28 nm CMOS process with an active area of 0.026 mm2. …”
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Injury burden in individuals aged 50 years or older in the Eastern Mediterranean region, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019
Published 2022“…<h3>Background</h3><p dir="ltr">Injury poses a major threat to health and longevity in adults aged 50 years or older. …”
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The impact of counseling on nutritional status among hematopoietic stem cell recipients: results of a randomized controlled trial
Published 2019“…Studies assessing malnutrition rates in HSCT showed that malnutrition rates are low at admission (ranging between 4 and 6%), elevated at hospital discharge (ranging between 35 and 60%), and gradually decreases post discharge [2, 3]. A prospective cohort study suggested that even though patients had improved quality of life, physical activity levels, and lean body mass post HSCT, they did not regain their pre-HSCT levels 100 days post transplantation compared to admission. …”
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Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats
Published 2013“…This study investigates the effect of the aqueous extract of the aerial part of T. porrifolius on lipemia and appetite regulation using a rat model. Food intake, abdominal fat percentage, blood lipid profile, liver weight and liver enzymes were assessed following 4 weeks of extract intake via drinking water (50, 100, or 250 mg/kg body weight) in standard high-carbohydrate and high-fat dietary conditions. …”
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
Published 2023“…In addition, a combination of other comorbidities and old age appears to increase the risk of mortality from COVID-19.…”
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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
Published 2020“…Deep bisulfite sequencing of single rDNA molecules in human sperm revealed that methylation does not only depend on donor's age, but also depend on the region and sequence context (A vs. G alleles). Both average rDNA methylation of all analyzed DNA molecules and the number of fully (>50%) methylated alleles, which are thought to be epigenetically silenced, increase with donor's age. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. …”
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…ConclusionCAN was associated with increased glycemic variability with less time in euglycemia attributed to a greater time in hyperglycemia but not hypoglycemia.…”
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…</p><h3>Conclusion</h3><p dir="ltr">CAN was associated with increased glycemic variability with less time in euglycemia attributed to a greater time in hyperglycemia but not hypoglycemia.…”
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins
Published 2012“…We hypothesized that neoadjuvant and adjuvant therapy should improve the survival probability in these patients. Methods This was a retrospective review of a prospective database of patients resected for gallbladder cancer (GBC) and cholangiocarcinoma (CC). …”
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