Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults by Khaddaj, Rashel

“…When vitamin D was considered as continuous variable, each unit increase in vitamin D levels was associated with a lower depression prevalence (OR=0.87; 95% CI:0.79-0.95, p=0.005) and when compared to those insufficient, those deficient were 4 times more likely to suffer from depression (OR=4.47, 95% CI:1.39-14.38,p=0.012) Nevertheless, these significant results were lost with further adjustment for BMI, MeDi adherence and physical activity: continuous vitamin D: OR=0.90; 95% CI: 0.81-1.01, p=0.08, deficient versus insufficient:OR=2.18; 95% CI: 0.56-8.47,p=0.259). After three-months supplementation of 50,000IU, vitamin D levels increased to 51.41 ±11.27ng/ml in the supplemented group and to24.95 ±6.45ng/ml in placebo group (p=0.00). …”
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