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Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
Published 2021“…Importantly, SESN2 silencing, unlike thapsigargin, caused a dramatic decrease in protein expression and phosphorylation of Akt, a critical pro-survival hub and component of the AMPK/Akt/mTORC1 axis. …”
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Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells
Published 2023“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild‐type CaM protein in the presence of Ca<sup>2+</sup>. …”
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Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…Stretching the RPV for 10 minutes significantly decreased phosphorylation of LKB1, AMPK, and eNOS, while APN significantly increased p-LKB1, p-AMPK, and p-eNOS in stretched vessels. …”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…In treated rat carcinomas, we found significant caspase-3, Bax, and Bax/Bcl-2 expression increases; on the other side, a significant down-regulation of Bcl-2, Ki67, CD24, ALDH1, and EpCam expressions and MDA levels. When compared to control specimens, evaluation of epigenetic alterations in rat tumor cells in vivo showed significant dose-dependent decrease in lysine methylation status of H3K4m3 and H3K9m3 and dose-dependent increase in lysine acetylation in H4K16ac levels (H4K20m3 was not changed) in treated groups. …”
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Data-Efficient Wheat Disease Detection Using Shifted Window Transformer: Enhancing Accuracy, Sustainability, and Global Food Security
Published 2025“…To enhance interpretability, Grad-CAM visualization techniques were applied, confirming model reliability. …”
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Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine
Published 2024“…Furthermore, we have utilized seven Explainable AI methodologies: Vanilla Gradients (VG), Guided Backpropagation (GBP ), Integrated Gradients ( IG), Guided Integrated Gradients (GIG), SmoothGrad, Gradient-weighted Class Activation Mapping (GCAM), and Guided Grad-CAM (GGCAM) for interpretability examination, aiding in the advancement of dependable and credible automation of healthcare detection of glaucoma.…”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
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Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
Published 2009“…Results showed that 50mg/kg and 100mg/kg caused 20.87 and 80.10%, respectively, compared to 41.70% for cimetidine at 11.5mg/kg BW dose. …”
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Deep Learning for Dynamic Wildlife Monitoring: A Real-Time Approach
Published 2025“…The parameters of the fine-tuned YOLOv11 decreased by 30% relative to the previous version, resulting in a very small model size of 5.5 MB and reduced processing time. …”
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
Published 2014“…The diameter and length of the Pipeline Embolization Device were measured at both time points and compared for determination of the device changes. …”
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