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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
Published 2009“…The inotropic response to maximal β-adrenergic stimulation was reduced by ≈54% in isolated hypertrophied hearts, along with a ≈32% decrease in subsarcolemmal cAMP levels in hypertrophied myocytes. …”
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Decreased phosphodiesterase activities in cardiac hypertrophy
Published 2007“…Cyclic nucleotide-gated (CNG) channels were used to monitor cAMP. The whole cell patch-clamp technique was used to record the associated CNG current (ICNG) and ICa,L. …”
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Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes
Published 2005“…Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
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Children safety risk factors in Khorasan Razavi province
Published 2015“…The study focused on rural roads in Khorasan Razavi province. Data came from police records and forensic medicine processed from 2010 to 2015. …”
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Embedding and global stability in periodic 2-dimensional maps of mixed monotonicity
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Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
Published 2009“…Results showed that 50mg/kg and 100mg/kg caused 20.87 and 80.10%, respectively, compared to 41.70% for cimetidine at 11.5mg/kg BW dose. …”
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Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome
Published 2020“…</p><h3>Patient concerns</h3><p dir="ltr">In this report, we present a 46-years-old previously healthy female who came with a 1-month history of a right upper quadrant pain and pruritis. …”
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Essays on international environmental policy
Published 2009“…My second essay, which is entitled "A Trade-Environment Coalition Came", deals with interconnections between international environmental problems and trade blocks in a multilateral context. …”
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
Published 2014“…The diameter and length of the Pipeline Embolization Device were measured at both time points and compared for determination of the device changes. …”
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New media and new practices of exploitation
Published 2015“…If he was alive, he would be responsible to analyze new exploitation mechanisms came into our lives through the introduction of new technologies, especially new media.We need to handle the new media and exploitation issues through four key terms: Posession, censorship, exploitation and political content production. …”
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