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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Published 2021“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Tailoring optical absorption in silicon nanostructures from UV to visible light: A TDDFT study
Published 2016“…Our main findings are that: (i) The oscillator strength as a function of length is quadratic at small lengths, and then increases linearly. (ii) The exciton binding energy is seen to decrease by approximately 45% from 0.67 eV to about 0.3 eV with length increase, for a nanostructure with a cross-section diameter of approximately 12 Å. …”
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Allergenicity of roasted peanuts treated with a non-human digestive protease
Published 2015“…Samples with lower in vitro IgE-binding were used for human skin prick tests (SPTs) in peanut allergic individuals. …”
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Tailoring of the thermal, mechanical and dielectric properties of the polypropylene foams using gamma-irradiation
Published 2016“…This study investigate the influence of gamma-irradiation (GI) doses from 0 up to 50 kGy on the polypropylene (PP) foams, mainly the impact on their structural and physical properties. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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Effect of Hyperglycemia on eNOS function in EPCs
Published 2020“…Results showed that both acute and chronic hyperglycemia showed a trend towards decrease in phosphorylation of eNOS and Akt. In addition, ROS formation was increased following 24hr compared to NG. …”
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Binding energy, structural, and dielectric properties of thin film of poly(aniline-co-m-fluoroaniline)
Published 2018“…The permittivity of copolymer PA-co-m-FA50 has a higher value than polyaniline in the high-frequency regime and decreases with the increase of frequency. The composition of each copolymer has been confirmed by binding energies of C-C, C-N, and C-F in the XPS study. …”
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Use and assessment of “e-plastics” as recycled aggregates in cement mortar
Published 2019“…The obtained results, for all RPs, (especially those of 7.5% and 10%) exhibited an increase in the CS of the specimens by 15.4% and 7.8%, respectively, with the MoE decreased in both cases by 18.1% and 23.8%, respectively. …”
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Evaluating the Short-Term Sustainability of Shared E-Scooters: A Usage-Centered Approach
Published 2023“…The need for regular collection and distribution of shared e-scooters leads to higher environmental, social, and economic ramifications when personal and shared e-scooters are utilized at the same rate.…”
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Cardiac Myosin Binding Protein-C in Sprague Dawley (SD) Rats exposed to Sub-Chronic oral dose of Cadmium Chloride
Published 2021“…The data demonstrated that cadmium decreased cMyBP-C at the protein level and downregulated its expression at the gene level. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Missense mutations in the POU homeodomain (POUH) of HNF1A hinder binding to the DNA, thereby leading to a dysfunctional protein. …”
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
Published 2022“…Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. …”
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Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Supplementation Alters Gut Microbiome and Corrects Dyslipidemia in Rats.
Published 2019“…Wistar rats were offered a chow maintenance diet (CMD; CON group) or the same CMD ration with cholesterol (1.5% w/w) and cholic acid (0.5% w/w) added to induce hypercholesterolemia (day 1 to day 24). …”
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