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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
Published 2019“…Baseline urinary LH concentrations, expressed as the mean � SD for each individual, were within the acceptable physiological range (7.11 � 5.42 IU/L). …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…MethodThe study comprised fully-vaccinated naïve individuals (VN; n = 596) who had no history of SARS-CoV-2 infection, and received two doses of either BNT162b2 or mRNA-1273, and naturally infected individuals who had a documented history of SARS-CoV-2 infection and no vaccination record (NI cohort; n = 218). …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…MethodThe study comprised fully-vaccinated naïve individuals (VN; n = 596) who had no history of SARS-CoV-2 infection, and received two doses of either BNT162b2 or mRNA-1273, and naturally infected individuals who had a documented history of SARS-CoV-2 infection and no vaccination record (NI cohort; n = 218). …”
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Advanced Hard Ctings: Towards A Whole New World
Published 2014“…METHODS: Three different thin hard nitrogen-rich coatings were mechanically, microstructurally, and thermally characterized: (i) a 2.5 micron-thick nano-layered CrN-NbN, (ii) a 11.7 micron-thick monolayer TiAlN, and (iii) a 2.92 micron-thick multilayer AlTiCrxNy. …”
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The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis
Published 2023“…There are only a few studies on humans suggesting that statins might also decrease TMAO, but their results are not unanimous. …”
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Published 2020“…Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1. …”
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Awareness of disabilities in pharmacy program recruitment material: are we doing enough?
Published 2020“…Introduction: Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats.
Published 2020“…CsA increased blood pressure (by 46mmHg) and decreased creatinine clearance (by 49%, all P<0.05). …”
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Improved properties of Al-Si3N4 nanocomposites fabricated through a microwave sintering and hot extrusion process
Published 2017“…In this study, nano-sized Si3N4 (0, 0.5, 1.0 and 1.5 vol%)/Al composites were fabricated using a powder metallurgy method involving microwave sintering technique followed by hot extrusion. …”
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Mn-ferrite based solar thermochemical water splitting cycle: A thermodynamic evaluation
Published 2019“…allied with the Mn-ferrite was observed to be increased as the PO2 was decreased from 10?1 to 10?5 atm and the TH was upsurged from 1500 to 2100 K. …”
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Aluminum nitride (AlN) reinforced electrodeposited Ni-B nanocomposite coatings
Published 2020“…The corrosion resistance could be credited to the presence of inactive and insulating AlN nanoparticles that filled the existing defects in Ni–B matrix and subsequently decreased the active area exposed to the corrosive electrolyte (3.5 wt.% NaCl).…”
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Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo)
Published 2014“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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