A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”

The Effect of the Variation of the Modulus of Subgrade Reaction on the Design of Large Shallow Foundations by Al Kaaby Al Zoaby, Hassan

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Breaking the barriers towards large-scale microalgae-based bio-hydrogen production by Isra Koko (22631396)

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial by Hourani, R.

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Parallel multi-voltage power minimization in VLSI circuits. (c2013) by Younes, Rabih Halim

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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. …”
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The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018) by El Jbeily, Elie

“…Following the coincubation of SF cells with Z-VAD and HuArgI (Co)-PEG5000, failure of Z-VAD to decrease arginine depletion-induced cell death was shown. …”
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Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death by Alayan, Moustapha

“…This implies that arginase-induced cell death is autophagy-mediated. Overall, these findings suggest that [HuArgI(Co)-PEG5000] is a potent therapeutic agent for breast cancer, leveraging the autophagy pathway to selectively induce cytotoxicity in ASS1-expressing breast cancer cells. …”
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The Effect of Soy Isoflavones on Steroid Metabolism by Amanda C. Swart (18153814)

“…In addition, 3βHSD2 was inhibited perhaps accounting for decreased A4 levels observed in females. The decreased DHEAS and A4 levels together with the inhibition of the 17,20 lyase activity of CYP17A1, may impact production of androgens in clinical conditions associated with androgen excess.…”

Innovative strategies to reduce traffic related injuries and deaths in youth by Joanne Banfield (19794507)

“…<p dir="ltr">Road traffic injuries are the leading cause of death among young people, aged 15-29 years (1). It is generally accepted that the high rate of adolescent injuries may be due to a variety of factors. …”

Hippocampal Programmed Cell Death after Status Epilepticus by Abi-Habib, Ralph J.

“…To investigate potential mechanisms that may underlie SE-related neuronal injury, we studied the occurrence of programmed cell death (PCD) in the hippocampus in the kainic acid (KA) model. …”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems by Raka Jovanovic (17947838)

“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”

Enhanced optical properties of <i>β</i>-Ga₂O₃-_<em>x</em>S_<em>x</em>S: A DFT study by G.B. Eshonqulov (22927297)

“…Here, we conduct systematic density functional theory calculations to study the effect of sulfur doping on the electronic and optical properties of <i>β</i>-Ga₂O₃. We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …”

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…This study aims to explore the cell death mechanism induced by [HuArgI(Co)-PEG5000] and its potential association with ferroptosis, a newly identified iron-dependent form of regulated cell death characterized by ROS accumulation and lipid peroxidation. …”
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …”

Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures by Elmootassem, Ruba A.

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Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 by Mokdad, Ali H

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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches by Roba Shady (22048043)

“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”

Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy by Samson Mathews Samuel (18808246)

“…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …”