Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains by Riachi, Naji J.

“…These results are consistent with the hypothesis that the rats' resistance to MPTP neurotoxicity is to some extent a property of their unique brain endothelium which has high MAO activity.…”
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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …”

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial by Hourani, R.

“…BACKGROUND AND PURPOSE: There is a paucity of data regarding the incidence of structural brain lesions in children with new-onset unprovoked seizures. …”
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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States by Yahya, Fares

“…In this paper, we present a method to quantify the coupling between brain regions under vigilance and enhanced mental states by utilizing partial directed coherence (PDC) and graph theory analysis (GTA). …”
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Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury by Fazle Rakib (5768069)

“…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …”

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development by Sahar I. Da’as (9631717)

“…Assessment of zebrafish neuromuscular responses revealed epileptic-like movements at early development, followed by seizure-like behavior, loss of touch response, and hypotonia, mimicking the clinical phenotype human patients. Altogether, we report a novel pathogenic PGAP3 variant associated with unique phenotypic hallmarks, which may be related to the gene’s novel role in brain morphogenesis and neuronal wiring.…”

RHO A versus RHO C. (c2014) by Dimassi, Saleh B. Al

“…Malignant astrocytomas are associated with high mortality rates; these tumors are highly invasive into adjacent areas of the normal brain. It has been established that Rho family of GTPases play a central role in regulation of cell migration and invasion. …”
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α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain by Eid, Fady

“…In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…”
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Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy by Yahya, Fares

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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Yadav, Santosh K.

“…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …”
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Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration by Milane, Aline

“…Methods: We have investigated the transport of bromocriptine through the blood-brain barrier (BBB) in a MPTP model to understand the influence of the dopaminergic degeneration on ABCB1 and ABCG2. …”
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Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury by Judith, Nwaiwu

“…WD has been shown to impair cognitive function, decrease the brain's capacity to compensate for insult by affecting recovery as well as induce metabolic syndrome (MetS) which may be a risk factor for poor TBI prognosis. …”
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Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy by Fazle Rakib (5768069)

“…Our results revealed that the total lipid and total protein content decreased significantly in the hippocampus, corpus callosum and thalamus after brain injury. …”

Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury by Sebnem Garip Ustaoglu (18460611)

“…This study reports the time-dependent contextual and structural effects of TBI on hippocampal brain tissue. A mild form of TBI was induced in 11-week old male Sprague Dawley rats by weight drop. …”

Dissecting the signaling pathways regulating the vascular endothelial growth factor (VEGF) in brain tumor cells. (c2017) by Nicolas, Samer Michel

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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000) by Jabre, Mazen Gerges

“…Parkinson's disease (PO) is a neurodegerative disorder predominantly characterized by the progressive loss of dopaminergic cells in the substantia nigra pars compacta (SNPC). …”
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Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy by Khoury, Reine

“…In old animals, damaged proteins accumulate in neurons since autophagy, a catabolic process responsible for organelle and protein degradation, decreases. …”
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Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization by Adrián Martín‐Segura (18615133)

“…Furthermore, in vivo inhibition of Cyp46A1, an enzyme involved in brain cholesterol loss with age, improved insulin signaling. …”

Expression of 3-Methylcrotonyl-CoA Carboxylase in Brain Tumors and Capability to Catabolize Leucine by Human Neural Cancer Cells by Eduard Gondáš (18877708)

“…When 13C6-leucine was offered, it led to an increased appearance of the heavier citrate isotope with a molar mass greater by two units in the culture media. …”

Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain by Mohamed H. M. Ali (5768066)

“…The results suggest that a good therapeutic strategy should include a mechanism that provides protective effect from brain swelling (edema) and neurotoxicity by scavenging the lipid peroxidation end products.…”