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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
Published 2025“…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …”
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Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
Published 2009“…Methods: We have investigated the transport of bromocriptine through the blood-brain barrier (BBB) in a MPTP model to understand the influence of the dopaminergic degeneration on ABCB1 and ABCG2. …”
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HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
Published 2021“…<p dir="ltr">Diabetes mellitus is associated with increased risk of erectile dysfunction. Penile prosthesis implantation is an efficient therapeutic option for erectile dysfunction, but not without risk, as infection remains a prominent concern. …”
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Large-scale triaxial and box testing on railroad ballast: a review
Published 2019“…The target of this paper is to present a concise review of the extensive literature presented on the mechanical behavior of railroad ballast using large scale triaxial and box testing. …”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”
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MEFood: A Large-Scale Representative Benchmark of Quotidian Foods for the Middle East
Published 2023“…To make food recognition systems feasible for the Middle Eastern region, we present a large-scale dataset (MEFood) of commonly consumed food items in the Middle East, thereby providing a dataset for current development and establishing a benchmark for future research. …”
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"Large-signal analysis of class-A vaccum triode push-pull output stage"
Published 2005“…For small amplitude signals, the degrading components are very small; they monotonically increase with large input tones. The parameters of the model can readily be determined using simple calculations.…”
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A Low Cost, Large Bandwidth Patch Antenna design for utilization in Frequency Diverse Arrays
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A survey of transformers and large language models for ECG diagnosis: advances, challenges, and future directions
Published 2025“…Despite the increasing adoption of these methodologies, a comprehensive survey systematically examining transformer and LLM-based approaches for ECG analysis is absent from the literature. …”
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Phosphorus supplementation increases thermic response to glucose solution in healthy lean subjects
Published 2013“…We hypothesised that the addition of P to a glucose load would enhance ATP production resulting in an increase in TEF. …”
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