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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000)
Published 2000“…The management of this disease is symptomatic, mainly based on the use of levodopa. Due to the high incidence of adverse effects associated with its chronic use, alternative treatments based on the direct-acting dopamine agonists have been used. …”
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Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy
Published 2021“…Fourier Transform Infrared (FTIR) imaging spectroscopy were used to collect chemical images from control and 3 hrs post-TBI (Marmarou model was used for the TBI induction) rat brains and adjacent sections were treated by hematoxylin and eosin (H&E) staining to correlate with the disruption in tissue morphology and injured brain biochemistry. …”
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Metformin inhibits 2D and 3D motility in astrocytoma cancer cells. (c2014)
Published 2016“…Hence, our study shows that Metformin could be used as an anti-metastatic drug in brain tumor.…”
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Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…Physical exercise is known to enhance learning and memory formation in the brain. These positive outcomes are mediated through the induction of the expression of a growth factor, brain derived neurotrophic factor (BDNF), in the hippocampus. …”
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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
Published 2019“…In this paper, we present a method to quantify the coupling between brain regions under vigilance and enhanced mental states by utilizing partial directed coherence (PDC) and graph theory analysis (GTA). …”
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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
Published 2020“…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …”
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When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
Published 2021“…BACKGROUND AND PURPOSE: There is a paucity of data regarding the incidence of structural brain lesions in children with new-onset unprovoked seizures. …”
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Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization
Published 2019“…<div><p>In the brain, insulin plays an important role in cognitive processes. …”
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Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury
Published 2021“…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Glioblastoma multiforme (GBM) is a highly aggressive glioma arising in the central nervous system accounting for more than 70% of all brain tumors. Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. …”
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Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
Published 2009“…Conversely, ABCG2 expression studied on brain capillaries from MPTP-treated mice was decreased (1.3-fold, p<0.05) and ABCB1 expression increased (1.43-fold, p<0.05) as an off-setting of brain transport. …”
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RHO A versus RHO C. (c2014)
Published 2016“…In this study we aim to look at the role both Rho A and Rho C play in protrusion formation where we found that upon RhoA knockdown protrusions are no longer formed, using 2D time lapse microscopy that shows the depletion of RhoA and RhoC leads to the decrease in 2D motility, RhoA knockdown decreases adhesion of cells in contrast RhoC knockdown increases adhesion of astrocytoma, and FRET based biosensors. …”
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Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress
Published 2021“…In addition, the MAPK/ERK pathway has been extensively studied and targeted for therapies. In addition, a decrease in the hippocampal brain derived neurotrophic factor (BDNF) protein level has been reported in postmortem human brains of depressed patients. …”
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