Showing 1 - 20 results of 24 for search '(( decrease heat resistance ) OR ( ((decrease therapeutic) OR (degrader therapeutics)) options ))', query time: 0.12s Refine Results
  1. 1

    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

    Published 2019
    “…We identified γ-secretase inhibitor (LY411575) as a potent regulator of osteoblastic differentiation of hBMSC that may be useful as a therapeutic option for treating conditions associated with ectopic bone formation.…”
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    DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation by Abdelilah Arredouani (10914455)

    Published 2019
    “…<p>Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. …”
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    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

    Published 2023
    “…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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  4. 4

    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

    Published 2023
    “…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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    Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue by Ali Tiss (437068)

    Published 2014
    “…<p dir="ltr">Obesity is characterized by a chronic low-grade inflammation and altered stress responses in key metabolic tissues. Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …”
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    Welding of Semiconductor Nanowires by Coupling Laser-Induced Peening and Localized Heating by Kelly M. Rickey (19568770)

    Published 2015
    “…The morphology results show that laser peening can decrease porosity and bring nanowires into contact and pulsed laser heating fuses those contacts. …”
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    Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review by Muhammad Asim (2235472)

    Published 2023
    “…This study presents the evaluation of performance parameters and the manufacturing aspects of microchannel heat exchangers. This study also examines how microchannel heat exchangers are affected by several parameters, including the type of working fluid used, Brownian motion, geometry of the channel, Reynolds number, Nusselt number, Knudsen number, wall resistance of the channel, the effect of gravity, and inlet and outlet arrangement for fluid. …”
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    Heat transfer measurements of Polyalpha-Olefin- boron nitride nanofluids for thermal management and lubrication applications by Ahmad K. Sleiti (14778229)

    Published 2020
    “…Two competing phenomena affect the heat transfer performance: the increase/decrease in resistance to thermal diffusion sublayer when thermal conductivity increases and viscosity decreases, respectively. …”
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    Thermally Conductive Polyethylene/Expanded Graphite Composites as Heat Transfer Surface: Mechanical, Thermo-Physical and Surface Behavior by Patrik Sobolčiak (4401364)

    Published 2020
    “…<p dir="ltr">Composites of high-density polyethylene (HDPE) and expanded graphite (EG) are prepared for heat exchangers in multi-effect distillation (MED) desalination. …”
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    Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes by Mohammad Amir Khan (23770803)

    Published 2025
    “…These results point to a scalable approach for developing lightweight corrosion resistant thermal management composites that can be used in the design of energy efficient wall panels and heat-dissipative building materials.…”
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    Isolation and study of Lipase activity of an olive oil degrading Thermoactionomyces SP. (c2002) by Al Khudary, Rami

    Published 2002
    “…This lipolytic enzyme showed resistance to boiling and to a wide range of metallic 10ns and inhibitors. …”
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    Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

    Published 2021
    “…However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic options. Development of targeted therapies for TNBC requires better understanding of biology and signaling networks that promote disease progression. …”
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    Dicarbonyl stress, protein glycation and the unfolded protein response by Naila Rabbani (291722)

    Published 2022
    “…An optimized inducer of Glo1 expression, trans-resveratrol and hesperetin combination, normalized increased MG concentration, corrected insulin resistance and decreased low grade inflammation in overweight and obese subjects. …”
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    Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior by Parker West (17268946)

    Published 2021
    “…The decreased corrosion resistance was attributed to inhomogeneous passive film formed across the weld due to zonal heterogeneities. …”