Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…We identified γ-secretase inhibitor (LY411575) as a potent regulator of osteoblastic differentiation of hBMSC that may be useful as a therapeutic option for treating conditions associated with ectopic bone formation.…”

Curcumin and Derivatives in Nanoformulations with Therapeutic Potential on Colorectal Cancer by Sourour Idoudi (14153457)

Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications by Gulab Sher (12984698)

“…Nevertheless, it promises to provide novel insight needed for utilizing these alterations as potential diagnostic, prognostic markers, predict treatment efficacy, as well as therapeutic agents. …”

Safety and effectiveness of interference RNA (RNAi) based therapeutics in cardiac failure: A systematic review by Muhammad Nabeel Saddique (19757076)

“…</p><h3>Conclusion</h3><p dir="ltr">RNAi therapeutics are novel treatment option for improving cardiac function because their high target specificity, ability to target genes that conventional drugs struggle to reach and potential for long-lasting effects. …”

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover by Naila Rabbani (291722)

“…Further research to decrease protein glycation in plants may lead to improved plant growth and assist the breeding of plant varieties resistant to environmental stress and senescence—including plants of commercial ornamental and crop cultivation value.…”

Studies on Natural Extracts as Inhibitors of Mild Steel Corrosion in 1M HC1 Solution by Shanableh, Alaa

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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines by Ismail, Jana

“…Cannabidiol (CBD) is one of the most abundant and commonly used cannabinoid of the Cannabis plant. Unlike tetrahydrocannabinol (THC), it lacks psychoactive properties, and thus it is considered to be a uniquely attractive cannabinoid for study. …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden by Monika, Rawat

“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
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Effect of water extract of Althaea officinalis flowers on inflammation, gastric ulcer, bacterial activity, platelet aggragation, glycemia, and lipidemia. (c2006) by Hage-Sleiman, Rouba

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Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats by Awkar, Nai

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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

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Removal of bacterial contaminants and antibiotic resistance genes by conventional wastewater treatment processes in Saudi Arabia: Is the treated wastewater safe to reuse for agricu... by Al-Jassim, Nada

“…This study aims to assess the removal efficiency of microbial contaminants in a local wastewater treatment plant over the duration of one year, and to assess the microbial risk associated with reusing treated wastewater in agricultural irrigation. …”
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Pharmacophore-Model-Based Virtual-Screening Approaches Identified Novel Natural Molecular Candidates for Treating Human Neuroblastoma by F A Dain Md Opo (14123109)

“…<div><p>The mortality of cancer patients with neuroblastoma is increasing due to the limited availability of specific treatment options. Few drug candidates for combating neuroblastoma have been developed, and identifying novel therapeutic candidates against the disease is an urgent issue. …”

System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases by Md. Saddam Hossen (18278698)

“…Advances in tumor diagnosis, innovative immune therapeutics, and checkpoint inhibitors-based treatment options improved the survival rate of patients with RCC accompanied by different risk factors. …”

Bone-targeted therapies in metastatic castration-resistant prostate cancer by El-Amm, Joelle

“…While several radiopharmaceuticals were approved for pain palliation in mCRPC including strontium and samarium, alpharadin is the first radiopharmaceutical to show significant overall survival benefit. Contemporary therapeutic options including enzalutamide and abiraterone have effects on pain palliation and SREs as well. …”
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Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…<p dir="ltr">Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. …”

1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH by Elhilali, Mostafa

“…PRX302 could offer an interesting therapeutic option for patients with LUTS 2ry to BPH.…”
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Aprocitentan: a new emerging prospect in the pharmacotherapy of hypertension by Lina Naseralallah (14146465)

“…It delivers exciting prospects for future therapeutic options in the setting of RH and expands insights into its pathophysiology. …”

Epigenetic control of inflammation in Atopic Dermatitis by Sabah Akhtar (5809925)

“…A thorough understanding of epigenetic remodeling of inflammation in AD has the potential of opening avenues for novel diagnostic, prognostic and therapeutic options.…”

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway by Kirti.S. Prabhu (17191231)

“…<p dir="ltr">Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. The high mortality associated with this malignancy indicates the need for new therapeutic interventions with fewer side effects. …”