Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS by Anna Halama (545988)

“…<p dir="ltr">Background: Plasma elevated levels of branched chain amino acids (BCAA) and aromatic amino acids (AAA) have been associated with obesity and insulin resistance, but their relationship to stimulated insulin resistance (IR) in PCOS and in response to exercise is unknown. …”

Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS by Myint Myint Aye (6404327)

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies by Sabah Nisar (12561961)

Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes by Fakhoury, H.

“…This study investigates the effect of Phenylbutyric Acid (PBA), a chemical chaperone and a potential mediator of PTEN activity, on glucose uptake in differentiated 3T3-L1 adipocytes. …”
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Genotypic and phenotypic characterization of Candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin by Toutounji, Maggie

“…Recently reports of resistance to caspofungin have been reported mainly through mutations in the FKS encoded subunits of glucan synthase at hot spot 1 (amino acids 641 to 649, FSTLSLRDP) and hot spot 2 (amino acids 1357 to 1364, DWIRRYTL). …”
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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines by Ismail, Jana

“…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. …”
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Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride by A. Bahgat Radwan (9631720)

Genotypic and phenotypic characterization of candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin. (c2018) by Toutounji, Maggie Nazih

“…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Muhanad Alhujaily (11630107)

“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”

Development of eco-friendly coating for the fabrication of high performing loose nanofiltration membranes for dye-contaminated wastewater treatment by Abedalkader Alkhouzaam (15842647)

“…<p>This study introduces highly efficient loose nanofiltration (LNF) membranes developed through a green synergistic combination of tannic acid (TA) and polyvinyl alcohol (PVA), aimed at addressing the complex challenge of dye/salt fractionation in wastewater treatment. …”

Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure, Dyslipidemia, and Low-Grade Inf... by Naila Rabbani (291722)

“…These findings suggest tRES-HESP counters MG accumulation and protein glycation, decreasing activation of the unfolded protein response and expression of TXNIP and TNFα, producing reversal of insulin resistance. tRES-HESP is suitable for further evaluation for treatment of insulin resistance and related disorders.…”

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature by Maha Sellami (4351159)

“…Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …”

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy by Ajaz A. Bhat (12984701)

“…The complex and dynamic interactions of the secreted cytokines, chemokines, growth factors, and their receptors mediate chronic inflammation and immunosuppressive TME favoring tumor progression, metastasis, and decreased response to therapy. …”

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…<p><strong>Poster by Imran Ramzan, Moira Taylor, Kenneth Smith, Dan Wilkinson, Philip Atherton, and Iskandar Idris (University of Nottingham)</strong></p> <p>Background: Recent studies have identified branched chain amino acids (BCAAs; isoleucine, leucine and valine) as potential biomarkers of, and being involved in, the pathogenesis of type 2 diabetes mellitus (T2DM), insulin resistance (IR) and obesity. …”

Phenotypic and cell wall proteomic characterization of a DDR48 mutant candida albicans strain by El Khoury, Pamela

“…Cell wall proteins are the most important among these factors, being the first elements contacting the host. Ddr48 is a cell wall protein consisting of 212 amino acids. …”
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Phenotypic and proteomic characterization of Dbr48, a candida albicans cell wall protein. (c2018) by Salameh, Carell C.

“…The most important virulence factors and antigenic determinants are the cell wall proteins as they are the first elements contacting the host. Ddr48 is a cell wall protein consisting of 212 amino acids. …”
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Cell surface proteome characterization of the Candida albicans DSE1 mutant. (c2011) by Zohbi, Racha M.

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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Despite the recent advances, many children continue to suffer from refractory and relapsed diseases, and they often develop metastatic tumors resistant to standard treatments. Amplification of MYC-N proto-oncogene is highly associated with clinically aggressive disease, recurrence and treatment failure. …”
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Muscle protein anabolism in type 2 diabetes by Bassil, Maya S.

“…In contrast, their protein anabolic response to hyperaminoacidemia suggested that ample amino acid administration, especially branched chain amino acids might overcome such insulin resistance. …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009) by Daher, Jalil Y.

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