Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells by Haidar, Fatemah

“…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …”
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E3 Ubiquitin Ligase <i>TRIP12</i> Controls Exit from Mitosis via Positive Regulation of <i>MCL-1</i> in Response to Taxol by Kripa S. Keyan (17807771)

Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy by Khoury, Reine

“…In old animals, damaged proteins accumulate in neurons since autophagy, a catabolic process responsible for organelle and protein degradation, decreases. …”
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The therapeutic potential of matcha tea: A critical review on human and animal studies by Sara Sokary (17337724)

The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models by Al Toufaily, Sahar

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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…Hypoxia-inducible factor (HIF) mediates a broad, conserved adaptive response to hypoxia, and the HIF pathway is a potential therapeutic target in cerebral ischemia. …”
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The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications by Naushad Ahmad Khan (6406973)

“…Some studies showed that TBI is a risk factor for different NDs. In terms of therapeutic potential, EVs outperform the alternative synthetic drug delivery methods because they can transverse the blood–brain barrier (BBB) without inducing immunogenicity, impacting neuroinflammation, immunological responses, and prolonged bio-distribution. …”

Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …”

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)

“…Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …”

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation by Kodappully S. Siveen (4246150)

“…Challenging lung airway epithelial cells (AECs) with LBCs decreased (by more than 50%) transepithelial resistance (TER) denoting barrier function alteration. …”

Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) by Khalil, Nathalie

“…Therefore, there’s a need for more effective and selective therapeutic approaches for targeting PC. In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

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Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress by Houbeika, Rouba

“…Our results suggest that different components of DCOE are responsible for its preventative effects as compared its therapeutic effects. …”
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation by Abdelilah Arredouani (10914455)

“…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …”

Adipocyte Enhancer-binding Protein-1 Promotes Macrophage Inflammatory Responsiveness by Up-Regulating NF-κB via IκBα Negative Regulation by Majdalawieh, Amin

“…Upon stimulation, IκB subunits become phosphorylated, ubiquitinated, and subsequently degraded, allowing NF-κB subunits to translocate to the nucleus and bind as dimers to κB responsive elements of target genes. …”
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Investigating the Properties of Electrodeposited of Ni-P-ZrC Nanocomposite Coatings by Osama Fayyaz (17017686)

“…<p dir="ltr">Superior corrosion resistance along with higher mechanical performance is becoming a primary requirement to decrease operational costs in the industries. …”

Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites by Mehdi Soleymani (3347741)

“…<div><p>Tungsten carbide (WC) and its composites are typically associated with high hardness and high wear resistance, posing challenges in conventional machining processes like turning. …”

1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH by Elhilali, Mostafa

“…The IPSS still showed a decrease of 4.3 points at 2 years post-treatment. However, no clear dose response was observed and Qmax did not increase in this study. …”
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Percutaneous Aspiration Irrigation Drainage Technique in the Management of Septic Arthritis in Children by Hayek, Toni

“…The draining system was removed when clinical improvement (namely apyrexia) and the decrease of biological inflammatory response were obtained. …”
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