-
1
Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
Published 2021“…Upregulation of β1-AR receptor transcripts was noted in diabetic hearts at 4 weeks along with an increase in cAMP levels and an upregulation in the ejection fraction and fraction shortening. …”
Get full text
Get full text
Get full text
Get full text
article -
2
StarD13
Published 2020“…StarD13 is a tumor suppressor and a GTPase activating protein (GAP) for Rho GTPases. …”
Get full text
Get full text
Get full text
Get full text
article -
3
-
4
Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…We have assessed the relationship between CAN and extensive measures of glucose variability (GV) in patients with type 1 and type 2 diabetes.</p><h3>Methods</h3><p dir="ltr">Participants with diabetes underwent continuous glucose monitoring (CGM) to obtain measures of GV and the extent of hyperglycemia and hypoglycemia and cardiovascular autonomic reflex testing.…”
-
5
Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…We have assessed the relationship between CAN and extensive measures of glucose variability (GV) in patients with type 1 and type 2 diabetes. MethodsParticipants with diabetes underwent continuous glucose monitoring (CGM) to obtain measures of GV and the extent of hyperglycemia and hypoglycemia and cardiovascular autonomic reflex testing. …”
Get full text
Get full text
Get full text
article -
6
Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
Published 2021“…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.…”
-
7
Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis
Published 2022“…<h3>Objective</h3><p dir="ltr">The main aim is to compare the risk of severe hypoglycemia associated with the modified-release (MR) gliclazide against glimepiride in diabetic older adults. </p><h3>Methods</h3><p dir="ltr">All older adult diabetic patients who attended the emergency department (ED) between the 1st of Aug. 2017 and the end of Mar 2020 on gliclazide MR or glimepiride are included in two cohorts. …”
-
8
-
9
iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion
Published 2022“…</p><h3>Conclusions</h3><p dir="ltr">IR-iPSCs generated from offspring of diabetic patients confirm that oxidative stress and increased lactate secretion, associated with IR, are inherited in this population, and may place them at a high risk of T2D. …”
-
10
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
Published 2014“…In the present study, we investigated the role of StarD13 in colon cancer. When overexpressed, StarD13 was found to lead to a decrease in cell proliferation in colon cancer cells. …”
Get full text
Get full text
Get full text
Get full text
article -
11
HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
Published 2021“…<p dir="ltr">Diabetes mellitus is associated with increased risk of erectile dysfunction. …”
-
12
-
13
-
14
The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013)
Published 2013Get full text
Get full text
masterThesis -
15
Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…Al-Siddiqi (Hamad Bin Khalifa University)</strong></p> <p>Background: Impaired insulin secretion contributes to the pathogenesis of diabetes mellitus type 1 (T1DM) through autoimmune destruction of pancreatic β-cells and the pathogenesis of diabetes mellitus type 2 (T2DM) through β-cell dedifferentiation and other mechanisms. …”
-
16
-
17
DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma
Published 2012“…Knocking down StarD13 using siRNA led to a decrease in cell death and an increase in cell viability, proving that StarD13 is indeed a tumor suppressor in astrocytomas. …”
Get full text
Get full text
Get full text
article -
18
Association of Diabetes Duration and Diabetes Treatment with the Risk of Hepatocellular Carcinoma
Published 2010“…CONCLUSIONS: Diabetes appears to increase the risk of HCC, and such risk is correlated with a long duration of diabetes. …”
Get full text
Get full text
article -
19
StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion
Published 2014“…We observed that, while the level of StarD13 expression decreases in cancer tissues compared to normal tissues, it increases as the grade of the tumor increased. …”
Get full text
Get full text
Get full text
article -
20
Immunoprofile of childhood diabetes
Published 2023“…Despite having distinctly different pathologies, both types of diabetes are associated with defects in immune regulation that mediate sensitivity to insulin. …”