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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Further, mutational analysis revealed a requirement for both cleavage sites to be intact for increased cleavage rate. Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases
Published 2008“…Purpose Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase in wound complications has been observed in patients who undergo surgery while receiving BV. …”
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Intelligent Rapidly-Exploring Random Tree Star Algorithm
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Effect of heating rate on the pyrolysis of camel manure
Published 2022“…The results indicated that the increase in heating rates increased the starting and ending temperatures (decomposition) of manure components. …”
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On the effects of user ratings on the profitability of cloud services
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The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase
Published 2008“…It increases 4-fold the rate of protein renaturation in vitro by the DnaK chaperone machine, suggesting that it cooperates with DnaK for the optimal expression of several cytoplasmic proteins.…”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…For extension (%) at peak load, a decreasing trend was found vs. stretch rate (R2 = 0.81; two-tailed p value = 0.037) where increasing the displacement rate from 1 mm/min to 500 mm/min corresponds to a 22% decrease in the relative elongation of the mesh. …”
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An optimal formulation for test scheduling network-on-chip using multiple clock rates
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Monitoring the variation of soil quality with sewage sludge application rates in absence of rhizosphere effect
Published 2020“…The dose-dependent improvement of organic matter content was the most significant event that reflected sludge application rates, and consequently influenced other soil properties. …”
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins
Published 2012“…One hundred fifty-seven patients underwent resection for primary GBC (n = 63) and CC (n = 94). Fisher’s exact test, Student’s t test, the log-rank test, and a Cox proportional hazard model determined significant differences. …”
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
Published 2024“…A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …”
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Reaction Kinetics of Carbon Dioxide in Aqueous Blends of N-Methyldiethanolamine and L-Arginine Using the Stopped-Flow Technique
Published 2019“…The experiments were performed over a temperature range of 293 to 313 K and solution concentration up to one molar of different amino acid/amine ratios. The overall reaction rate constant (kov) was found to increase with increasing temperature and amine concentration as well as with increased proportion of L-Arginine concentration in the mixture. …”
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
Published 2021“…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.</p><h3>Methods</h3><p dir="ltr">A case-control study of aged-matched T2D (n = 23) and control (n = 23) subjects who underwent a hyperinsulinemic clamp over 1-hour to hypoglycemia(<40mg/dl) with subsequent timecourse of 4-hours and 24-hours. …”