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9 large » _ large (Expand Search), a large (Expand Search)
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. Our findings suggest that direct activation of GLP-1R by Ex-4 reduces OA-induced steatosis in HepG2 cells by reducing fatty acid uptake and transport via FABP1 downregulation.…”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …”
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Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…A CSTR nutrient-recovery line on digested <i>Scenedesmus</i> recovered 68 % N and 72 % P via struvite, reducing synthetic fertilizer ∼35 %; flue-gas CO<sub>2</sub> (12 % v/v) lifted biomass 22 % and reduced carbon-supplement cost 86 %. …”
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Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors
Published 2022“…<div><p>Cofactor flavin adenine dinucleotide (FAD), a compound with flavin moiety and a derivative of riboflavin (vitamin B2), is shown to bind to Sox9 (a key transcription factor in early pancreatic development) and, subsequently, induce a large increase in markers of pancreatic development, including Ngn3 and PTF1a. …”
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A Low Cost, Large Bandwidth Patch Antenna design for utilization in Frequency Diverse Arrays
Published 2023Get full text
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…In vitro experiments also showed that 15-HETE induced HREC migration and tube formation in a NOX-dependent manner. Taken together our data suggest that 12/15-LOX is implicated in DR via a NOX-dependent mechanism.…”
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Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods
Published 2025Get full text
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
Published 2013Get full text
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Investigation of an integrated hydrogen production system based on nuclear and renewable energy sources: a new approach for sustainable hydrogen production via copper-chlorine ther...
Published 2011“…Hydrogen production via thermochemical water decomposition is a potential process for direct utilization of nuclear thermal energy to increase efficiency and thereby facilitate energy savings. …”
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Investigation of an integrated hydrogen production system based on nuclear and renewable energy sources: a new approach for sustainable hydrogen production via copper–chlorine ther...
Published 2011“…Hydrogen production via thermochemical water decomposition is a potential process for direct utilization of nuclear thermal energy to increase efficiency and thereby facilitate energy savings. …”
Get full text
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