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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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COVID-19 may have increased global support for universal health coverage: multi-country observational study
Published 2023“…In this study, it was specifically examined if the pandemic changed support for governmental intervention in healthcare as a proxy to support for universal health coverage (UHC). It also examined which psychological factors related to the socioeconomic interdependence exposed by the pandemic may be associated with a potential change.…”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
Published 2013Get full text
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masterThesis -
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Biomarkers of COVID-19 severity may not serve patients with polycystic ovary syndrome
Published 2021“…Whilst the comparison with absolute disease-free normality is relevant, an increasing proportion of the population have insulin resistant states with associated metabolic conditions; an example of such a metabolic condition is polycystic ovary syndrome (PCOS) where it has been shown that protein expression patterns may differ compared to those without PCOS [3]. …”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …”
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Performance and microbial community variations of anaerobic digesters under increasing tetracycline concentrations
Published 2017“…Instead, a significant increase in propionic acid was observed in the reactor subjected to the highest concentration of tetracycline (20 mg/L). …”
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…Consistent with this, P-gp function was also increased by 1.5-fold and riluzole brain disposition was decreased by 1.7-fold in mSOD1 mice. …”
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Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…SFN also enhanced clearance of proteins cross-linked by transglutaminase which otherwise increased in senescence. …”
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
Published 2023“…</p><h3>Conclusion</h3><p dir="ltr">This systematic review and meta-analysis suggest that hypertension may not be the only risk factor associated with the increased mortality rate during the COVID-19 pandemic. …”
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Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures
Published 2024Get full text
doctoralThesis -
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The Effect of Soy Isoflavones on Steroid Metabolism
Published 2019“…In addition, 3βHSD2 was inhibited perhaps accounting for decreased A4 levels observed in females. The decreased DHEAS and A4 levels together with the inhibition of the 17,20 lyase activity of CYP17A1, may impact production of androgens in clinical conditions associated with androgen excess.…”
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Enhanced optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>-<sub><em>x</em></sub>S<sub><em>x</em></sub>S: A DFT study
Published 2025“…Here, we conduct systematic density functional theory calculations to study the effect of sulfur doping on the electronic and optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>. We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …”
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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
Published 2024“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”
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Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
Published 2019“…Assays for cell proliferation, migration and tubulogenesis were also performed. We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …”
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There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East an...
Published 2019“…Similar increases were also evident in EVs originating from platelets, erythrocytes, granulocytes, and leukocytes. …”
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Shear Strength Behavior of Tire Shred-Dune Sand Admixtures
Published 2025Get full text
doctoralThesis