Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro by Rizk, Sandra

“…Introduction: AML, considered as the most common type of leukemia, is characterized by the dysregulation between alive and Abstracts Clinical Lymphoma, Myeloma & Leukemia September 2017 - S279 dead cells, due to either alteration in tumor suppressor genes or activation of oncogenes, resulting in the accumulation of immature cells in the bone marrow. …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…Andrographolide (AG) is a plant-derived compound that was reported to induce apoptosis and autophagy in acute myeloid leukemia cell lines. Objective: The aim of this study was to investigate the possible synergism between topotecan and andrographolide in acute myeloid cells in vitro, to enhance the effect of low doses of topotecan in controlling cancer progression. …”
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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling by Sabah Akhtar (5809925)

“…However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a mostly incurable malignancy of plasma cells. …”

Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells by Tawil, Mirna

“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages by Salman M. Toor (8854751)

“…<p dir="ltr">Myeloid-derived suppressor cells (MDSCs) are a heterogenous population of cells that have been implicated in the development of an immunosuppressive environment, which promotes tumorigenesis and tumor progression. …”

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…In this study, we showed for the first time that arginine deprivation using a recombinant human arginase induces ferroptosis, an autophagy-mediated type of cell death in AML cells. Acute Myeloid Leukemia (AML) poses significant challenges due to its unfavorable prognosis and limited treatment options, particularly in elderly patients. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

“…<h3>Background</h3><p dir="ltr">Chronic myeloid leukemia is defined as the neoplastic development of mostly myeloid cells in the bone marrow. …”

Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death by Alayan, Moustapha

“…Inhibition of autophagy decreased sensitivity to arginase-induced cytotoxicity in all cell lines, and hence reversed cell death. …”
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro by Rizk, Sandra

“…However, the effect of the beta subtype on cancer cells is still not well studied. The present study aims to investigate and compare the effect of beta and gamma tocotrienols on the proliferation of acute myeloid leukemia cells, namely KG-1, in vitro. …”
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Effect of Anthrax Lethal Toxin on Activation of MAPK Pathway and Autophagy in AML Cell Lines by Soukarieh, Rania

“…Anthrax lethal toxin has been extensively studied for its antitumor effect and showed potency against the majority of acute myeloid leukemia cell lines. In addition to that, previous data have shown that autophagy is activated in most AML cell lines. …”
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Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Gunjan Dagar (9339276)

“…CAR-T therapy has achieved FDA approval for treating blood cancers like B-cell acute lymphoblastic leukemia, large B-cell lymphoma, and multiple myeloma by targeting CD-19 and B-cell maturation antigens. …”