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Showing 1 - 20 results of 942 for search '(( significant ((a decrease) OR (mean decrease)) ) OR ( significant challenge increases ))', query time: 0.12s Refine Results
  1. 1

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review by Kaiprath Puthiyapurayil Haseeba (21392966)

    Published 2025
    “…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …”
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    Challenges and practices identification in complex outsourcing relationships: A systematic literature review by Ghulam Murtaza Khan (12024573)

    Published 2022
    “…However, by virtue of its complexity, the complex outsourcing typically necessitates the interactions among various stakeholders from diverse regions and cultures, making it significantly more challenging to manage than traditional outsourcing. …”
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

    Published 2019
    “…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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    The Role of Project Management Soft Skills in Increasing Project Success by AL AWABDEH, JOYCE YOUSEF

    Published 2017
    “…As the world economy shifts towards an increasingly globalised market, the degree of competition becomes a more significant challenge which organisations face. …”
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

    Published 2022
    “…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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    Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

    Published 2023
    “…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

    Published 2019
    “…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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    Challenges of morbid obesity in gynecological practice by Albert A. Opoku (17019078)

    Published 2023
    “…Surgery in the patient with morbid obesity is associated with several logistical challenges as well as increased surgical and peri-operative risks and increased cost.…”
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

    Published 2014
    “…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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    The Challenges of Corporate Governance Systems for Construction Project Management by Alzarooni, Khalid

    Published 2014
    “…However, despite the growth in the area, the industry continues to face different challenges. Researchers have associated the challenges with poor corporate governance. …”
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    Analysing the State of Inclusive Education in China: Challenges and Perspectives by Zainab Merchant

    Published 2025
    “…However, challenges remain in implementing inclusive practices and delivering quality education to children with special needs. …”
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    An investigation into the impact of COVID-19 on school leadership in Dubai by Abukhalaf, Siham

    Published 2022
    “…In an attempt to gain an insight into their experiences, the aim of this small-scale research project was to explore the challenges that principals have encountered during the COVID-19 pandemic and the solutions they made to overcome these challenges. …”
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