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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake
Published 2002“…The effect of high-frequency ultrasound on doxorubicin (DOX) release from Pluronic micelles and intracellular DOX uptake was studied for promyelocytic leukemia HL-60 cells, ovarian carcinoma drug-sensitive and multidrug-resistant (MDR) cells (A2780 and A2780/ADR, respectively), and breast cancer MCF-7 cells. …”
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Ultrasound Triggered Release of Estrone- Targeted Liposomes
Published 2017Get full text
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Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study
Published 2021“…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. All the patients in the study group had a reduction of >6 points in the NIH-CPSI score, indicating a robust treatment response. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Investigating the acoustic release of doxorubicin from targeted micelles
Published 2013“…The maximum amount of release (14%) was measured at 5.4 W/cm². A power density threshold at approximately 0.55 W/cm² exists below which no statistically significant release was observed. …”
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Encapsulation and Release of Calcein from Herceptin-conjugated eLiposomes
Published 2023Get full text
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Hemodynamics of small aneurysm pairs at the internal carotid artery
Published 2012“…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
Published 2016Get full text
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Light-Responsive Metal-Organic Frameworks (MOFs) For Doxorubicin Controlled Release
Published 2023Get full text
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The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes
Published 2018Get full text
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
Published 2018Get full text
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Ultrasound-responsive Nanocarriers in Cancer Treatment: a review
Published 2021“…The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. …”
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
Published 2016Get full text
doctoralThesis