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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Since SLFN11 has been reported as an interferon inducible gene, and interferon is secreted during an active anti-tumor immune response, we investigated the in vitro effect of IFN-γ on SLFN11 expression in breast cancer cell lines. …”
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Potential anti-inflammatory, anti-ulcerogenic and antioxidant activity of Nasturtium officinalis water extract
Published 2010“…For the anti-ulcerogenic activity, pre-treatment of fasted rats with100 and 250mg/kg body weight demonstrated significant protection (32.1% and 51% respectively) against ethanol-induced gastric ulcer, compared to 10mg/kg cimetidine (50.24%) and 3mg/kg omeprazole (47.81%)3. …”
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Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
Published 2009“…The same doses were used to test for anti-inflammatory activity against edema induced in hind paw by carrageenan. …”
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Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
Published 2020“…<p>Oleuropein and hydroxytyrosol, as major compounds of olive leaves, have been reported to exert numerous pharmacological properties, including anticancer, antidiabetic, and anti-inflammatory activities. The purpose of this study is to evaluate and compare the protective effect of oleuropein- and hydroxytyrosol-rich extracts, derived from olive leaves, on high-fat diet-induced lipid metabolism disturbance and liver injury in rats. …”
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Board changes and CEO turnover
Published 2014“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome
Published 2011“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Chemical composition, antioxidant and anti-inflammatory activity evaluation of the lebanese propolis extract
Published 2019“…Measurement of paw thickness in carrageenan-induced paw edema in mice and pathologic assessment of inflammation in paw sections were used to judge the anti-inflammatory properties of propolis. …”
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Biological and anti-inflammatory evaluation of two thiazole compounds in RAW cell line
Published 2012“…Our data demonstrated that CX-32 and CX-35 significantly blocked prostaglandin production induced during inflammatory cellular stress, possibly acting through specific COX-2 inhibition; confirmation of this hypothesis requires further investigation.…”
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Anti-Angiogenic Effects of Phytochemicals on miRNA Regulating Breast Cancer Progression
Published 2020“…In the current article, we identify different miRNAs that regulate tumor angiogenesis in the context of oncogenic signaling and metabolic reprogramming in ECs and review how selected phytochemicals could modulate miRNA levels to induce an anti-angiogenic action in breast cancer. …”
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Nasturtium officinalis water extract. (c2009)
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…ResultsUp to six months, VN individuals had a significantly higher NtAb and anti-S-RBD IgG antibody responses compared to NI individuals. …”
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Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study
Published 2022“…Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …”
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Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
Published 2020“…The inhibition of NHE1 has been demonstrated to reduce cardiac hypertrophy but the mechanism that contributes to the anti-hypertrophic effect of NHE1 inhibition still remains unclear. …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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