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Factors Influencing the Magnitude and Clinical Significance of Drug Interactions Between Azole Antifungals and Select Immunosuppressants
Published 2006“…Differences in metabolism and in the inhibitory potency of cytochrome P450 3A4 and Pglycoprotein influence the onset, magnitude, and resolution of drug interactions and their potential effect on clinical outcomes. …”
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Non-Newtonian Effects in a Fluid-Structure Interaction Model for Atherosclerosis
Published 2009“…In this paper we study the blood-plaque interaction using a fluid-structure interaction model. …”
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Analysis and Design of Circular Shafts Using Finite Element Method
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Detection of statistically significant network changes in complex biological networks
Published 2017“…<h3>Background</h3><p dir="ltr">Biological networks contribute effectively to unveil the complex structure of molecular interactions and to discover driver genes especially in cancer context. …”
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The Effect of the Variation of the Modulus of Subgrade Reaction on the Design of Large Shallow Foundations
Published 2022“…The design of mat foundations is a common application of soil-structure interaction. In a typical mat foundation design, the structure element (mat) is modeled as either rigid or flexible plate overlying an elastic subgrade. …”
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Board changes and CEO turnover
Published 2014“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Enhancing Arabic Reading Proficiency as a Second Language: Unveiling the Significance of Audiobooks for Middle School Students
Published 2024“…By understanding the benefits and limitations of audiobooks, instructors can effectively incorporate them into their curriculum, thereby promoting a more engaging and interactive learning environment for Arabic language learners. …”
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The Development And Significance Of Business Intelligence (BI) Platforms In Facilitating The Decision-Making Process In Dubai Government Entities
Published 2022“…However, its application and benefits for the Dubai government entities for effective data management and decision making have not been investigated before. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome
Published 2011“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Malignant peritoneal mesothelioma interactome with 417 novel protein–protein interactions
Published 2024“…The MPeM interactome overlapped significantly with the malignant pleural mesothelioma interactome, revealing shared molecular pathways.…”
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Partnering for Sustainability: Parent-Teacher-School (PTS) Interactions in the Qatar Education System
Published 2021“…Furthermore, while almost all parents recognize the significance of parental involvement and show a high level of interest in being on the ‘Board of Trustees’, in reality, very few participate or volunteer in school activities, and they rarely visit classrooms or interact with teachers or schools, mainly due to their increasing job-related commitments. …”
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Essays on the effect of excess compensation and governance changes on firm value
Published 2012“…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …”
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The Interactions of Business Environment, Generic Strategy, Operations Strategy, and Business Performance in the Lebanese Industries
Published 2021“…The results confirmed the significance of the direct effects at the aggregate level. …”
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A Decision Modelling Approach for Perceived and Engaged Immersive Visual Interactive Applications on the Metaverse
Published 2024“…The results illustrate the effectiveness of the modelling approach and indicate that "spatial" and “haptics” are the most significant criteria in evaluating immersive visual interactive applications. …”
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …”
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Insights into the interaction between mineral formation and heavy metals immobilization, mediated by Virgibacillus exopolymeric substances
Published 2024“…Heavy metal pollution poses significant risks to both the environment and human health due to their toxicity, long residence times, and their ability to bioaccumulate and bio magnify across the food chain. …”
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