Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice by Zeeni, N.

“…In addition, a significant interaction was found between CCK administration and the HF diet, shown by an increased activation in the PVN, which suggests a decrease the inhibiting action of CCK. …”
Get full text
Get full text
Get full text
Get full text

Evaluation of waterpipe smoke toxicity in C57BL/6 mice model by Abi-Gerges, Aniella

“…Our results mainly showed a significant increase in urea serum levels (+28%) in SE mice along with renal pathological damage in both SE and DE mice compared to CON. …”
Get full text
Get full text
Get full text
Get full text

The Role of DJ-1 in the Glycation Process of Skin and Plasma Proteins in Mice Models by Abou Younes, Nour

“…Mice were then treated with ND-13 to identify through it the deglycase activity of DJ-1.Overall, the findings of this study indicate that the glycation process in the skin might need more than just a few weeks to form the early and intermediate glycation products, this was translated by the significant increase of DJ-1 levels after 8 weeks of treatment with an exogenous glycating agent compared to week 4. …”
Get full text
Get full text
Get full text

Board changes and CEO turnover by Dah, Mustafa A.

“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
Get full text
Get full text
Get full text
Get full text

Cafeteria diet-fed mice is a pertinent model of obesity-induced organ damage by Zeeni, Nadine

“…This study provides a novel dietary model in mice that mimics multi-organ physiologic alterations in humans secondary to obesity.…”
Get full text
Get full text
Get full text
Get full text

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Herein, we evaluated the in vivo effects of chronic administration of AB-FUBINACA on the hippocampus in mice. Our results revealed that the administration of AB-FUBINACA induced a significant impairment in recognition memory associated with histopathological changes in the hippocampus. …”
Get full text
Get full text
Get full text

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman Alzu'bi (18192898)

“…Herein, we evaluated the in vivo effects of chronic administration of AB-FUBINACA on the <u>hippocampus</u> in mice. Our results revealed that the administration of AB-FUBINACA induced a significant impairment in recognition memory associated with histopathological changes in the hippocampus. …”

Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice by Hedya Jemai (14571781)

“…Results showed that Cd induced a significant increase in liver injury biomarkers coupled with enhanced lipid peroxidation (MDA) and significant depletion of antioxidants (CAT and SOD). …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”

Vocal Changes in Patients With Polycystic Ovary Syndrome by Hannoun, Antoine

“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
Get full text
Get full text
Get full text

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish by Fatiha M. Benslimane (6695087)

“…The multi-mode (i.e., b-mode, m-mode, Pulsed Doppler, Tissue Doppler, etc.) small animal ultrasound systems in the market can be used for most <i>in vivo</i> cardiac disease models including mice, embryonic chick and zebrafish. These systems are also associated with significant costs. …”

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation by Mahéva Vallet (18456729)

“…At 52 weeks, Oc.S/BS did not differ between genotypes but single labelled perimeter (SL.Pm/B.Pm (%)) was significantly higher in Rin3⁻/⁻ mice (24.4 ± 6.4 vs. 16.5 ± 3.8, p = 0.003). …”

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

“…In this aggressive mouse model of breast cancer, loss of MMP-8 accelerated tumor onset even further, such that 90% of MMTV-PyMT; Mmp8-null female mice were tumor-bearing at the time of weaning. Throughout the 14 weeks of the model, tumor burden increased in homozygous Mmp8-null mice compared to Mmp8-wild-type and -heterozygote animals. …”

Gasoline fume inhalation induces apoptosis, inflammation, and favors Th2 polarization in C57BL/6 mice by Nour-Eldine, Wared

“…At the end of the study period, toxic and molecular mechanisms underlying the inflammatory, oxidative, and apoptotic effects triggered by gasoline vapors, were examined in the lungs and liver of gasoline-exposed (GE) mice. Static gasoline exposure induced a significant increase (+21%) in lungs/body weight (BW) ratio in GE versus control (CON) mice along with a pulmonary inflammation attested by histological staining. …”
Get full text
Get full text
Get full text
Get full text

Essays on the effect of excess compensation and governance changes on firm value by Dah, Mustafa A.

“…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …”
Get full text
Get full text
Get full text

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS by Anna Halama (545988)

“…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …”

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…Leaders’ capacity to think about abstract and complex ideas has long been acknowledged as essential to leadership tasks such as planning and analysis; however, because conceptualisation is often ambiguous and difficult to understand, many frameworks of leadership and change lack clarity on the actual significance of leaders’ conceptual skills when leading change. …”
Get full text

Swimming exercise improves short‐ and long‐term memories: Time‐course changes by Mahmoud A. Alomari (14780446)

“…In this investigation, changes in the spatial hippocampal memory following a time-course of swimming exercise training were examined. …”