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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Effect of Strain Fields on Frequency Band Gaps of Periodic Lattice-Based Metamaterials
Published 2024“…This work computationally investigates the effect of stretching strain fields on a hexagonal lattice-based metamaterial. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A Chip-Level BSOR-based linear GSIC multiuser Detector for Long-Code CDMA Systems
Published 2007Get full text
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Characterization and Modeling of Damage in Steel at Different Strain Rates
Published 2011Get full text
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Security Assessment of Low-Resource Edge Devices for IoT Systems
Published 2020Get full text
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Dynamic mechanical characterization and modelling of polypropylene based organoclay nanocomposite
Published 2015“…The experimental characterization was performed by using split Hopkinson pressure bars (SHPB), at different strain rates and temperatures. A significant increase of the yield stress of nanocomposite was shown with the present of organoclay, comparing to neat PP. …”
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Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population
Published 2015“…Potato-based chips and baked chips were found to contain 23% and 18% more acrylamide than corn-based chips and fried chips, respectively. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Computer vision syndrome among students during remote learning periods: harnessing digital solutions for clear vision
Published 2023“…Mother’s employment, having positive history of visual disturbances, and excess screen time were found to be significant predictors of CVS.</p><h3>Conclusion</h3><p dir="ltr">Health care providers in collaboration with teachers should provide parents with evidence-based strategies to prevent or minimize the digital eye strain among students. …”
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Memory synthesis for FPGA-Based reconfigurable computers
Published 2017“…With the advent of on-chip memories, a rich hierarchy of physical memories is now available on a Reconfigurable Computer (RC). …”
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