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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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A hybrid 3D CNN-LSTM model with soft spatial attention mechanism for accurate hyperspectral image classification
Published 2025“…This study introduces a hybrid deep learning model that combines 3D Convolutional Neural Networks (CNNs) with Long Short-Term Memory (LSTM) networks, incorporating residual connections and a soft spatial attention mechanism to overcome these limitations. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Significance of Avicennia Marina in the Arabian Gulf Environment: A Review
Published 2025“…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…”
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Hierarchical multi-head attention LSTM for polyphonic symbolic melody generation
Published 2024“…The model allows learning of long-term dependencies at different levels of abstraction, while retaining the ability to form inter-dependencies. …”
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Efficient self-attention with smart pruning for sustainable large language models
Published 2025“…However, their high computational demands result in significant environmental impacts, particularly in terms of energy and water consumption. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Agent Productivity Modeling in a Call Center Domain Using Attentive Convolutional Neural Networks
Published 2020“…We explore several designs for the classifier based on convolutional neural networks (CNNs), long-short-term memory networks (LSTMs), and an attention layer. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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FLACON: A Deep Federated Transfer Learning-Enabled Transient Stability Assessment During Symmetrical and Asymmetrical Grid Faults
Published 2024“…The proposed approach effectively incorporates cross-domain deep federated transfer learning (FTL) to leverage local operating data for TSA in a decentralized fashion. By introducing convolutional layers alongside multi-head attention mechanisms, the FLACON framework significantly improves learning efficiency across geographically distributed datasets. …”
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MACGAN: An All-in-One Image Restoration Under Adverse Conditions Using Multidomain Attention-Based Conditional GAN
Published 2023“…Furthermore, an ablation study is conducted to analyze the contributions of the discriminator and attention blocks within the MACGAN architecture. The results confirm that both components play significant roles in the effectiveness of MACGAN, with the discriminator ensuring adversarial training and the attention blocks effectively capturing and enhancing important image features.…”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
