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Improving text-to-image generation with object layout guidance
Published 2022“…To evaluate the performance of our approach, we use the COCO dataset and compare it with three baseline approaches, namely, sg2im, StackGAN and AttnGAN, in terms of image quality and user evaluation. According to the obtained assessment results, our object layout guidance-based approach significantly outperforms the abovementioned baseline approaches in terms of the accuracy of semantic matching and realism of the generated images representing the story text sentences.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Translation of atherosclerotic disease features onto healthy carotid ultrasound images using domain-to-domain translation
Published 2023“…<h3>Objective </h3><p dir="ltr">In this work, we evaluated a model for the translation of atherosclerotic disease features onto healthy carotid ultrasound images. </p><h3>Methods </h3><p dir="ltr">An un-paired domain-to-domain translation model – the cycle Generative Adversarial Network (cycleGAN) – was trained to translate between carotid ultrasound images of healthy arteries and images of pronounced disease. …”
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Quantitative imaging of lymph function
Published 2007“…NIR fluorescence imaging employed illumination of 780 nm excitation light (∼2 mW/cm2) and collection of 830 nm fluorescence generated from the imaging agents. …”
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MACGAN: An All-in-One Image Restoration Under Adverse Conditions Using Multidomain Attention-Based Conditional GAN
Published 2023“…The results confirm that both components play significant roles in the effectiveness of MACGAN, with the discriminator ensuring adversarial training and the attention blocks effectively capturing and enhancing important image features.…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…Real-world studies of crizanlizumab showed a reduction in complicated VOC events. The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. …”
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Exploring the Transformative Potential of Generative AI in Mechanical Engineering Education
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Privacy Preserving Cancellable Template Generation for Crypto-Biometric Authentication System
Published 2025“…Integrating cryptographic techniques with biometric modality has presented a dual-layered security mechanism, significantly mitigating the risk of biometric data breaches. …”
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Nonlinear analysis of shell structures using image processing and machine learning
Published 2023“…This is achieved by mapping shell deformations and stresses to a set of images that are used to train a conditional generative adversarial network. …”