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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
Published 2016“…Total average lymph node harvests were similar between the groups; however, there was an increase in the number of positive lymph nodes seen in the R1 group. Propensity matched analysis confirmed that R1 resection margin was significantly associated with reduced overall survival and increased overall, locoregional, and mixed tumor recurrence. …”
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Need for Affect, Problematic Social Media Use and the Mediating Role of Fear of Missing Out in European and Arab Samples
Published 2023“…</p><h3>Results </h3><p dir="ltr">Regression analysis results indicated that both affect approach and affect avoidance as part of the need for affect construct significantly predicted PSMU in both cultural contexts. …”
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Identifying organizational climate affecting learning organization
Published 2012“…It also identified the organizational climates that significantly affect a given LO dimension and their degree of influence. …”
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Artisanal fishing of spiny lobsters with gillnets — A significant anthropic impact on tropical reef ecosystem
Published 2015“…The study compared an area which was subjected to intense gillnet fishing against one were the practice was absent. The analysis of target species using nocturnal visual census demonstrated a significantly higher number of P. echinatus at the site where gillnet use was virtually absent within three sampled habitats, fringe, cave and soft bottom. …”
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
Published 2011“…This dissertation attempts to study the significance of staff professional development for educators and how it can affect students’ achievement. …”
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The Factors Affecting Project Success Criteria – Aviation projects
Published 2017“…These issues are impacting all parties and projects stakeholder’s .As UAE and all developing countries are affected by such issues , the necessity of studying the factors affecting the project’s success criteria considered vital and the requirement to overcome these risks become important to all parties. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”