Detection of statistically significant network changes in complex biological networks by Raghvendra Mall (581171)

“…<h3>Background</h3><p dir="ltr">Biological networks contribute effectively to unveil the complex structure of molecular interactions and to discover driver genes especially in cancer context. It can happen that due to gene mutations, as for example when cancer progresses, the gene expression network undergoes some amount of localized re-wiring. …”

Organic micropollutants in aerobic and anaerobic membrane bioreactors: Changes in microbial communities and gene expression by Harb, Moustapha

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Identification of Genes Associated with Familial Focal Segmental Glomerulosclerosis Through Transcriptomics and In Silico Analysis, Including RPL27, TUBB6, and PFDN5 by Mahmoud, Anfal

“…A comprehensive in silico analysis was performed using the GSE99340 data set from Gene Expression Omnibus (GEO) comparing gene expression in glomerular and tubulointerstitial tissues from FSGS patients (n = 10) and Minimal Change Disease (MCD) patients (n = 8). …”
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The Use of the Gene Expression Omnibus (GEO) Database to Study Gene Expression and Methylation Patterns in Cases of Preterm Birth and Associated Diseases by Tala Abuarja (17075070)

“…</p> <h3>Design</h3> <p>This is a retrospective study done to observe any reported significant changes in gene expression or methylation patterns between PTB, associated diseases, and full-term births (FTB).…”

Gene expression data analysis identifies multiple deregulated pathways in patients with asthma by Reem H. Alrashoudi (18629731)

“…The data highlight the multifactorial nature of asthma, but revealed no significant overlap with the gene expression profiles from different datasets interrogated in current studies. …”

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... by Masri, Oussama Samer

“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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Enhanced climate change resilience on wheat anther morphology using optimized deep learning techniques by Arifa Zahir (20748764)

“…<p dir="ltr">Wheat commands attention due to its significant impact on culture, nutrition, the economy, and the guarantee of food security. …”

Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”

iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes by Noura Aldous (15429873)

“…PPs generated from FOXA2–/–hiPSCs and WT controls were exposed to RNA-sequencing and miRNA-sequencing. Gene ontology (GO) and KEGG pathways analyses were performed on the differentially expressed genes (DEGs). …”

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer by Varun Sasidharan Nair (5396393)

“…To study the role of DNA methylation, we checked the promoter CpG methylation of ICs and ligands and found that only CTLA-4 and TIGIT, among other genes, were significantly hypomethylated in TT compared with NT. …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…”

Rescue cerclage by Khoury, Alfred

“…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …”
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STARD 13 in prostate cancer. (c2018) by Saab, Sahar S.

“…Proliferation and migration are known to be regulated by Rho family of GTPases. StarD13 is a GAP for Rho GTPases and has been previously described to be a tumor suppressor in astrocytoma, breast and colorectal cancer. …”
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Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy, Mallah

“…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? by Wahiba Elhag (5245547)

“…Mean HbA1c significantly decreased from 8.1%preop to 6.77%_{year 9}. …”

Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy... by Kazandjian, Chant

“…Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”

Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy Mallah (17831954)

“…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”

Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries by Mouyad Alsamara (17823668)

“…These findings have significant implications for labor markets and nationalization policies in the GCC countries.…”