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p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells
Published 2023“…These findings suggest that adding a p53 inhibitor to the differentiation media can significantly enhance the generation of monohormonal β-cells.…”
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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells
Published 2008“…These results suggest that WP1066 enhances T cell cytotoxicity against melanoma through inhibition of Tregs.…”
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Cactus-like nanothorn photoanodes for enhancing dye-sensitized solar cell efficiency
Published 2025“…<p dir="ltr">The surface area for dye adsorption in the photoanode layer is critical in enhancing the power conversion efficiency (PCE) of dye-sensitized solar cell (DSSC). …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome
Published 2020“…CDH10 overexpression significantly reduces cellular movements in breast cancer cell lines and prevents the hypoxia-mediated increase in cell motility. …”
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Sesamum indicum (sesame) enhances NK anti-cancer activity, modulates Th1/Th2 balance, and suppresses macrophage inflammatory response
Published 2020“…JAM assay was performed to examine the cytotoxic activity of NK cells against YAC-1 tumor cells. Results: Sesamum indicum significantly enhanced splenocyte proliferation in a dose-dependent manner. …”
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Kidney Ensemble-Net: Enhancing Renal Carcinoma Detection Through Probabilistic Feature Selection and Ensemble Learning
Published 2024“…It includes various subtypes, such as clear cell, papillary and chromophobe renal cell carcinomas, which are characterized by different cellular structures and behaviours. …”
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Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> and CD4...
Published 2019“…</p><h3>Results</h3><p dir="ltr">SM16 abrogates TGF-β-induced Treg generation in vitro but does not prevent global homeostatic expansion of CD4<sup>+</sup>T cell sub-populations in vivo. Instead, SM16 treatment causes expansion of a population of CD4<sup>+</sup>CD25<sup>−</sup>Foxp3<sup>+</sup> Treg-like cells without significantly altering the overall frequency of Treg in lymphoreplete naive and tumor-bearing mice. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells
Published 2023“…Moreover, Ea.hy926 cell viability was significantly reduced by 35% when treated with MGO; while cells treated with MSCs-CM (50%) were protected. …”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”
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Amniotic stem cells as a source of regenerative medicine to treat female infertility
Published 2022“…The therapeutic potential of these cells to restore or enhance normal ovarian function and pregnancy outcomes are highlighted in this study.…”
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Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis
Published 2021“…Vascular smooth muscle cells (VSMCs) are the predominant cell type in collateral arteries and respond to altered blood flow and inflammatory conditions after an arterial occlusion by switching their phenotype between quiescent contractile and proliferative synthetic states. …”