A long-lived cuprous bis-phenanthroline complex for the photodynamic therapy of cancer by Al Hageh, Cynthia

“…It was found that Cu(dsbtmp)2+ [dsbtmp = 2,9-disec-butyl-3,4,7,8-tetramethyl-1,10-phenanthroline] (compound 3), which possessed the longest excited state lifetime, exhibited significant in vitro photocytotoxicity on A375 (human malignant melanoma) and A549 (human lung carcinoma) cell lines. …”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications by Amr Nasr Fekry (22521185)

“…This research addresses critical knowledge gaps regarding living microalgae-mediated mercury removal and demonstrates <i>MIMA's</i> potential as a sustainable, efficient solution for mercury contamination in aquatic ecosystems, maintaining viability even under nutrient-limited conditions while effectively reducing mercury concentrations to near guideline values at the lowest initial level (10 μg/L).…”

Antibacterial Activities of Selected Pure Compounds Isolated from Gut Bacteria of Animals Living in Polluted Environments by Akbar, Noor

“…Using purified compounds, assays were performed to determine their antibacterial properties using serial dilution method, cytotoxic effects using lactate dehydrogenase release, and cell viability using MTT assay. The results revealed that the purified compounds exhibited significant antibacterial activities (p < 0.05) against selected Gram-negative (Pseudomonas aeruginosa) and Gram-positive bacteria (Streptococcus pyogenes) with effective MIC₅₀ and MIC₉₀ at μg concentrations, and with minimal effects on human cells as observed from LDH and MTT assays. …”
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Effective generation of functional pancreatic β-cells from human derived dental stem cells of apical papilla and bone marrow derived stem cells by Duaa Abuarqoub (6672434)

“…</p> <p>Results: Our results have shown that both SCAP and BM-MSCs were sequentially committed to definitive pancreatic endoderm, and β-cell like cells by upregulating the expression of FOXA2 and SOX17 significantly (p****<0.0000 and p***=0.0001) respectively. …”

An evaluation of sorter induced cell stress (SICS) on peripheral blood mononuclear cells (PBMCs) after different sort conditions - Are your sorted cells getting SICS? by Gerald Pfister (17075275)

“…However, majority of available cell sorters are pressurized, droplet-based systems, which apply significant environmental pressure and shear stress to cells during sorting. …”

Interventions for recurrent embryo implantation failure: An umbrella review by Abdulla Almohammadi (14158848)

“…The SRs often had a level of overlap of RCTs (median 33.3%), inconsistent definitions of RIF, and varied comparisons for the interventions. Considering the significant meta‐analytic evidence of high‐moderate GRADE strength: Granulocyte colony‐stimulating factor (G‐CSF) showed improvement in CPR in 9/13 (69.2%) MAs and LBR in 1/7 (14%); intralipid infusion showed improvement in CPR in 4/6 (57.14%) MAs and LBR in 3/4 (75%); peripheral blood mononuclear cells (PBMC) showed improvement in CPR in 4/8 (50%) MAs and LBR 3/5 (60%); platelet‐rich plasma (PRP) intervention showed improvement in CPR in 6/10 (60%) MAs and LBR in 1/5 (20%); human chorionic gonadotropins showed improvement in CPR in 3/3 (100%) MAs; growth hormone showed improvement in CPR in 1/1 (100%) MA; low molecular weight heparin showed improvement in CPR in 1/1 (100%) MAs and LBR in 1/2 (50%); hysteroscopy showed improvement in CPR in 1/2 (50%) MAs; and, intentional endometrial injury showed improvement in CPR in 3/4 (75%) MAs and LBR in 2/3 (66.66%).…”

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... by Masri, Oussama Samer

“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”

Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development by Al Saneh, Mounir

“…The aim is to look for significant differences in the behaviour of the CL/P patient-derived cells in vitro when compared to control cells from the healthy donor through the study of different mechanisms, including cell proliferation, cell migration and adhesion. …”
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Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells by Tahir Abdulrehman (8697696)

GATA3: Orchestrating cellular fate through differentiation and proliferation by Rim Bacha (14779420)

“…<u>Zinc finger proteins</u> are TFs responsible for maintaining the biological balance via coordinating development and functionality within the living cells. GATA<u> binding protein</u> 3 (GATA3), one of the zinc finger proteins, plays an essential role in driving differentiation and proliferation-related processes, thereby contributing to the regulation of the dynamism and productivity of living cells. …”

<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells by Nouralhuda Alateyah (21363215)

“…TI significantly suppressed BC cell growth, inhibited migration and invasion and induced apoptosis. …”

Thermodynamic Analysis of an Integrated Hydrogen Production System Based on Solar and Nuclear Energy Sources in the UAE by Babu, Binish Sam

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Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment by Alanod D. AlQahtani (18805930)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Mutation of the two residues in NLuc revealed a decreased but stable activity of the R162A, but not Q32A, mutant NLuc in live cell and in vitro assays performed using lysates prepared from cells expressing the proteins and with the furimazine substrate. …”

Anti-amyloid monoclonal antibody therapies in Alzheimer’s disease – a scoping review by Shahd Abubaker Elamin (22569539)

Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance by Lubna Therachiyil (4246156)

“…We have previously reported that exposure of OC cells to TCDD, an AhR activator, significantly modulated the expression of several genes that play roles in stemness and chemoresistance. …”

Differing endometrial expression of calcium modulating transient receptor potential channels by Maryam Ghavideldarestani (11862563)

“…<p dir="ltr">To the editor</p><p dir="ltr">Assisted reproductive techniques (ART) have increased the live birth success rate, but there is still a significant implantation failure rate. …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…”

Rescue cerclage by Khoury, Alfred

“…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …”
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