Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases by Kesmodel, Susan

“…Conclusion Neither the use of BV nor timing of BV administration was associated with an increase in complication rates. These data suggest that the combination of BV with neoadjuvant CTX in patients who have CRC liver metastases does not increase surgical complications. …”
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Combining Saliency with Prediction for Endoscopic Diagnosis by Rezk, Mahmoud

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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Estimating the Impact of Combined Horizontal and Vertical Curves on Drivers’ Perception by Alozn, Mohammad Essam

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis by Ahmad R. Al-Qudimat (17337808)

“…In addition, a combination of other comorbidities and old age appears to increase the risk of mortality from COVID-19.…”

Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis by Abdullah Bin Kamran (22565237)

Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease by Ramadan, Wijdan H.

“…For patients not sufficiently controlled on a single long-acting bronchodilator, a combination of different bronchodilators has shown a significant increase in lung function. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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Effective Approach for Increasing the Heteroatom Doping Levels of Porous Carbons for Superior CO2 Capture and Separation Performance by Abdelmoaty, Yomna H

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Thermo-economic Optimization of Hybrid Combined Power Cycles Using Heliostat Field Collector by Saghafifar, Mohammad

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Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19 by Matli, Kamal

“…Conclusion The use of combined anticoagulant and antiplatelet agents or TAC alone in hospitalised patients with COVID-19 was associated with a better outcome in comparison to PAC alone without an increase in the risk of major and minor bleeds. …”
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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system by Frank Schmidt (207186)

Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study by Alexandra E. Butler (6189536)

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy by Samson Mathews Samuel (18808246)

“…Additionally, treatment with metformin and 2DG (5 mM) inhibited the Akt/mTOR pathway and down-regulated the cell-cycle-related proteins such as p-cyclin B1 (S147) and cyclins D1 and D2 when compared to cells that were treated with either 2DG or metformin alone. Treatment with a combination of 2DG (5 mM) and metformin (2 mM) also significantly decreased cell proliferation, migration and tubulogenic capacity when compared to cells that were treated with either 2DG or metformin alone. …”

Optimal scheduling algorithm for residential building distributed energy source systems using Levy flight and chaos-assisted artificial rabbits optimizer by D., Sathish Kumar

“…The increase in demand for MicroGrids (MGs) is a significant factor in the provision of electricity in the future, mainly due to the use of renewable energy sources, which reduces the release of hazardous gases. …”
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Independent and Combined Effects of Antioxidant Supplementation and Circuit Resistance Training on Selected Adipokines in Postmenopausal Women by Ayoub Saeidi (17331085)

“…In contrast, omentin-1, ghrelin, adiponectin, and FGF21 significantly increased in EG and EMG (all p < 0.05) after CRT. …”

Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability by Abdelrahman Abushanab (17268940)

“…<p dir="ltr">The drastic increase in freshwater and ordinary Portland cement (OPC) consumption poses severe environmental and economic challenges worldwide. …”