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significant decrease » significantly increased (Expand Search), significantly increases (Expand Search), significant genes (Expand Search)
decrease ros » increased ros (Expand Search), decrease _ (Expand Search)
significant decrease » significantly increased (Expand Search), significantly increases (Expand Search), significant genes (Expand Search)
decrease ros » increased ros (Expand Search), decrease _ (Expand Search)
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Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros
Published 2021“…In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …”
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NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs
Published 2022“…Sera from SSc patients showed significant changes in the expression of a set of fibrosis/EndMT-associated microRNAs (miRNA), including miR-21, miR-92a, miR-24, miR-27b, miR-125b, miR-29c, and miR-181b, which resulted significantly upregulated as compared to healthy donors sera. …”
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Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia
Published 2019“…Sang mediates its anti-cancer activity by generation of reactive oxygen species (ROS) due to depletion of glutathione level in leukemic cell lines. …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Published 2018“…Furthermore, PACAP induced ROS through H₂O₂ production whereas pretreatment with NAC inhibitor decreased AKT and ERK phosphorylation, but not p38. …”
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Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties
Published 2022“…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. Additionally, only higher concentrations of OSEE were able to attenuate inhibition of proliferation induced by the ROS scavenger N-acetyl cysteine (NAC), indicating that the anti-proliferative effects of OSEE could be ROS-dependent. …”
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ASSOCIATION BETWEEN INSULIN RESISTANCE AND NITRIC OXIDE IN HUMAN RETINAL MICROVASCULAR ENDOTHELIAL CELLS IN VITRO
Published 2015“…This study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably reduced with insulin treatment after 1hour, 2 hours and 4 hours. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
Published 2016“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
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Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre...
Published 2022“…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …”
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THE ASSOCIATION BETWEEN SOFT DRINK CONSUMPTION AND BONE MINERAL DENSITY AMONG QATARI WOMEN: ANALYSIS OF QATAR BIOBANK DATA
Published 2019“…Reports from these studies presented conflicting findings. Some suggesting significant decreases in BMD levels due to soft drink consumption, while others find null associations. …”
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Do labor remittance outflows retard economic growth in Qatar? Evidence from nonlinear cointegration
Published 2022“…In particular, positive changes of remittance outflows exert a greater impact on non-oil real GDP per capita than negative changes. A larger increase in remittance outflows would lead to a decrease in the aggregate demand and produce a deflationary pressure. …”
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Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes
Published 2022“…In addition, DHA-treatment of hypoxic cells caused a significant reduction in the apoptosis rate and ROS production with decreased lipid peroxidation. …”
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Phase change materials for thermal energy storage applications in greenhouses: A review
Published 2022“…Greenhouses represent one of the largest energy-demanding sectors, requiring energy for indoor environment control for plant growth and crop yield. …”
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
Published 2015“…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …”
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
Published 2022“…Mitochondrial ATP production is the main source of reactive oxygen species (ROS) and hence the regulation of ROS becomes an important issue in maintaining optimal ANS functionality. …”
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Changing Trends in the Referral and Timing of Treatment for Congenital Cryptorchidism: A Single-Center Experience from Bosnia and Herzegovina.
Published 2019“…The analysis of the observed two periods (2008-2010 and 2015-2017) showed a statistically significant decrease in the mean referral age and the mean age at surgery over the last 5 years (2015-2017) (p = 0.007 and p = 0.003, respectively). …”
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Impact On Local Pearl Oyster Pinctada Radiata Exposed To Chronic Levels Of Chlorine
Published 2019“…Nevertheless, the experiment suggested that the size class of the considered oysters had a significant impact on mortality and growth, with larger specimens showing relatively lower performance than the smaller oysters. …”
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Preparation of Mesoporous/Microporous MnCo2O4 and Nanocubic MnCr2O4 Using a Single Step Solution Combustion Synthesis for Bifunction Oxygen Electrocatalysis
Published 2020“…Chronoamperometric (CA) runs for 24 h shows excellent stability of MnCo2O4 without any significant decrease in the current or potential value in ORR and OER. …”
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