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The lung protein that tells all
Published 2016“…<p dir="ltr">Researchers found that serum levels of surfactant protein D (SP-D), a protein that protects the lungs against pathogens and regulates inflammation, increased when patients with chronic obstructive pulmonary disease (COPD) experienced acute exacerbations. …”
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Anti-cancer Evaluation of Lebanese Cannabis Oil Extract on Lung and Breast Cancer Cells
Published 2021“…Western blot analysis showed significant increase in MAPK/ERK pathway and the autophagic marker LC3B. …”
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3
An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
Published 2025“…<p dir="ltr">In the field of medical imaging, deep learning (DL) techniques have made significant contributions to the detection and classification of various cancers. …”
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The anti-neoplastic activity of novel platinum II and IV complexes against A549 lung cancer cells
Published 2021“…Western blots experiments were also carried out to observe the effect of the drugs on key apoptotic proteins. Data revealed a significant drop in procaspase 3 and a significant increase in Bax/Bcl2 ratio, Cytochrome c, Parp and procaspase 8. …”
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5
Unravelling the predictors of late cancer presentation and diagnosis in Jordan: a cross-sectional study of patients with lung and colorectal cancers
Published 2023“…Conclusions This study highlights important factors associated with the late presentation and diagnosis of colorectal and lung cancers in Jordan. Investing in national screening and early detection programmes as well as public outreach and awareness campaigns will have a significant impact on early detection to improve treatment outcomes.…”
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Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways
Published 2022“…Treatment of rats with Pb for three consecutive days significantly increased the accumulation of Pb in lung tissues causing severe interstitial inflammation. …”
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Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published 2021“…<p dir="ltr">Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. …”
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The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells
Published 2020“…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …”
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9
The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells
Published 2021“…It also significantly increased Bax/Bcl2 ratio and PERK levels without affecting caspase-3 expression. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…Bisulfite-sequencing demonstrated 45.6% demethylation efficiency at the NY-ESO-1 gene promoter region and RT-qPCR analysis confirmed the significant induction of NY-ESO-1 at mRNA level (128-fold increase, *p < 0.050). …”
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Novel Platinum II and Platinum IV Complexes Exhibit An Anti-Neoplastic Potential Against A549 Cancer Cell Line
Published 2021“…Treatment with Pt II and Pt IV also showed significant amounts of free radical production and increased DNA damage. …”
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14
The effect of indoor air quality on health and performance of labors in joinery factories
Published 2020“…According to the International Agency for Research on Cancer (IARC), wood particles intervention the respiratory system, which decreases the lung capacity and causes signs such as, allergic reaction, irritation of eyes, nose, and throat, and cancer (Sawane & Sawane 2017). …”
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
Published 2015“…Several well-designed randomized trials confirmed that the synergistic effect of both drugs in combination was able to improve lung function and health-related quality of life without a significant increase in adverse effects. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Solar energy has the largest untapped reserve in energy and is one of the fastest emerging energy markets. …”
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Effect of consanguinity on birth weight for gestational age in a developing country
Published 2007“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Also, there was a significant decrease in p-Erk and p-Akt protein levels. …”
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
Published 2017“…After controlling for other sources of emissions, U.S. states that produce a larger share of renewable energy are found to have lower GHG emissions. …”
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
Published 2010“…Rationale: Vascular endothelial growth factor receptor (VEGFR) inhibition increases ceramides in lung structural cells of the alveolus, initiating apoptosis and alveolar destruction morphologically resembling emphysema. …”
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