Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions by Hemalatha Parangusan (6556133)

System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases by Md. Saddam Hossen (18278698)

The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach by Hatem, Zayed

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The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach by Hatem Zayed (835448)

Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase by Marta Cecchi (21363581)

“…We demonstrate here that dex significantly upregulates TDO in A375, a more aggressive melanoma cell line, confirming that dex effects are not limited to SK-Mel-28 cells. …”

The microbiome-lymphoma Axis: A systematic review and Meta-analysis of gut Dysbiosis pattern in diffuse large B-cell lymphoma by Sarah A. Elkourashy (21632903)

“…Increasing evidence suggests that gut dysbiosis may play a significant role in the pathogenesis of diffuse large B-cell lymphoma (DLBCL), the most common and aggressive subtype of non-Hodgkin lymphoma (NHL). …”

Chemical Composition, Antioxidant Capacity, and Anticancerous Effects against Human Lung Cancer Cells of a Terpenoid-Rich Fraction of Inula viscosa by Fatiha Seglab (22468265)

“…This study aimed to examine the potential anticancer properties of methanolic and aqueous extracts of stems and leaves of <i>I. viscosa</i> and its terpenoid-rich fraction against human lung cancer A549 cells. Results showed that the methanolic extracts of <i>I. viscosa</i> had significantly higher polyphenol and flavonoid content and radical scavenging capacity than the aqueous extracts. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…The transcriptomic profiling was performed using total RNA extracted from untreated, steatotic and Ex-4-treated steatotic, cells. We validated a subset of differentially expressed LncRNAs with qRT-PCR and identified the most significantly enriched cellular functions associated with the relevant LncRNAs, among them MALAT1. …”

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Further bioinformatic analysis employing Ingenuity Pathway Analysis revealed significant enrichment in BMS-833923-treated cells for a number of functional categories and networks involved in connective and skeletal tissue development and disorders, e.g., NFκB and STAT signaling. …”

Cathelicidin LL-37-induced transcriptome of human keratinocyte identifies chemokine CXCL10 link to T cell-mediated rosacea pathogenesis via JAK-1/STAT-1 pathway by Abdul W. Ansari (14557391)

“…While KEGG enrichment analysis revealed the activation of TNF signaling, IL-17 signaling, NF-kB signaling and chemokine signaling among the most significant pathways. …”

An integrated multi-omic approach demonstrates distinct molecular signatures between human obesity with and without metabolic complications: a case–control study by Fayaz Ahmad Mir (11828354)

Comprehensive analysis of LncRNAs expression profiles in an in vitro model of steatosis treated with Exendin-4 by Khaoula Errafii (10914446)

“…We validated a subset of differentially expressed LncRNAs with qRT-PCR and identified the most significantly enriched cellular functions associated with the relevant LncRNAs.…”

Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting by Shimaa Sherif (12862990)

“…Moreover, this 3 lncRNA signature showed additional prognostic significance in uterine corpus endometrial carcinoma and cervical squamous cell carcinoma and endocervical adenocarcinoma as compared to ICR.…”

MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the... by Radhakrishnan Vishnubalaji (3563306)

“…Concordantly, global gene expression profiling revealed significant enrichment in cholesterol biosynthesis pathway, and pathways related to enhanced cell movement and survival, whereas processes related to bone and connective tissue developments, cell death, apoptosis, and necrosis were downregulated. …”

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways by William J. Young (18426897)

“…In contrast for QRS, connective tissue components and processes for cell growth and extracellular matrix interactions are significantly enriched. …”

DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome by Yosra Bejaoui (8552574)

“…We could observe DNA methylation alterations at 61 CpG sites as well as 32 significant regions following a 5 Kb tiling analysis. …”

Date palm (Phoenix dactylifera L.) fruit's polyphenols as potential inhibitors for human amylin fibril formation and toxicity in type 2 diabetes by Ali Chaari (827168)

“…Recent studies suggested that a diet based on date fruits presents various health benefits, as these fruits are naturally enriched in plant polyphenols.</p><h3>Method</h3><p dir="ltr">In this study, we used a broad biophysical approach, using cell biology techniques and bioinformatic tools, to demonstrate that various polyphenols from date palm (<i>Phoenix dactylifera</i> L.) fruit significantly inhibited hIAPP aggregation and cytotoxicity.…”

Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer by Andrea Remo (447375)

“…The staining pattern of non-neoplastic mammary epithelial cells was used as a normal control. </p><h3>Results</h3><p dir="ltr">Using in-silico modeling of network-based strategy, we identified three top enriched MRs (NFAT5, CTNNB1 or β-catenin, and MGA) strongly linked to the IBC phenotype. …”

Development of a cancer metastasis-on-chip assay for high throughput drug screening by Lutfiye Yildiz Ozer (17732619)

“…Notably, MEK inhibitors were enriched in cluster cell invasion and intravasation. …”

Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches by ALHAJERI, RASHED ABDULLA

“…Solar energy has the largest untapped reserve in energy and is one of the fastest emerging energy markets. …”
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