Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone by Ilhame Diboun (3522413)

“…Additionally, methylation profiles in 11 regions showed Bonferroni-significant association with disease severity including six islands (located in VCL, TBX5, CASZ1, ULBP2, NUDT15 and SQSTM1), two gene bodies (CXCR6 and DENND1A), and 3 promoter regions (RPL27, LINC00301 and VPS29). …”

Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity by Rukaya Basala

“…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …”
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The efficacy of colchicine in the management of coronavirus disease 2019 by Mohamed Nabil Elshafei (9960500)

“…If colchicine proved to be effective, it would be a significant milestone in the management of COVID-19, a disease with limited available therapeutic options.…”

Cerebrospinal α‐Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort by Nour K. Majbour (8809316)

“…CSF oligomeric-α-synuclein levels appear to increase with diseases severity and reflect PD motor rather than cognitive trajectories. © 2021 The Authors. …”

Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman by Mhd Baraa Habib (11721774)

“…<p dir="ltr">Rheumatic mitral stenosis (MS) with significant calcification presents challenges for both surgical and transcatheter interventions. …”

Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity by Mohamed A. Elrayess (7956179)

“…Functional enrichment analysis revealed long-chain polyunsaturated fatty acids (n-3 and n-6) as the pathway exhibiting the most significant changes with increased disease severity in hypertensive patients (FDR = 0.07).…”

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort by Muneerah Smith (12542939)

“…As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. …”

Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity by Jamila, Al-Zadjali

“…Metabolic risk markers from fasting blood samples were analyzed, and data regarding disease severity indicators were collected. Findings indicated significant metabolic shifts in severe Long-COVID-19 cases, mainly a marked drop in HDL-C levels and a doubled increase in ferritin levels and insulin resistance compared to the mild cases and controls. …”
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …”

Detection of statistically significant network changes in complex biological networks by Raghvendra Mall (581171)

“…Several procedures have been recently proposed to detect sub-network differences in pairwise labeled weighted networks.…”

The Detection of Dysarthria Severity Levels Using AI Models: A Review by Afnan Al-Ali (16888695)

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Addiction to smartphones in Arabs is associated with severe depressive symptoms and insomnia: a cross-sectional study by Omar Gammoh (11819798)

Association of coronary artery disease and chronic kidney disease in Lebanese population by Milane, Aline

“…This correlation remained highly significant despite considerable inter-patient variability and was at its highest at the most advanced stages of both diseases. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

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Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage by Nour Majbour (3528548)

“…<h3>Background and Objectives</h3><p dir="ltr">Robust biomarkers that can mirror Parkinson disease (PD) are of great significance. In this study, we present a novel approach to investigate disease-associated α-synuclein (αSyn) aggregates as biomarkers of PD clinical stage.…”

Sugar-Sweetened Beverages Contribute Significantly to College Students’ Daily Caloric Intake in Jordan: Soft Drinks Are Not the Major Contributor by Hiba Bawadi (3436379)

“…Obesity is an independent risk factor for several chronic diseases. This study aimed to (1) assess the consumption level of SSBs among college students in Jordan and (2) examine the relationship of consumption level to body weight. …”

Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient by Tahir Shahzad (21842195)

“…However, concerns remain regarding the risk of decompensated cardiac function due to extreme tachycardia and severely elevated systemic blood pressure. In this case, a middle-aged male with a known history of coronary artery disease and congestive heart failure deteriorated significantly after ketamine was administered for sedation to facilitate a computed tomography pulmonary angiogram. …”

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene by Zalloua, Pierre

“…Type 1 diabetes (T1D) is a complex autoimmune disease. Several genetic loci have been implicated in the susceptibility to this illness. …”
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Coronary artery disease. (c2011) by Youhanna, Sonia C.

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