Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy by Abeer Qannan (14779192)

“…<div><p>Berardinelli–Seip congenital lipodystrophy type 2 (CGL2) is a very rare human genetic disorder with potential significance to the understanding of the pathobiology of aging. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl by MOHAMED, SHAMSELDIN SAEED

“…On the other hand, the same study proved that the grid system and the villa model are the main reason behind the urban sprawl of the city. …”
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Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling by Md Mizanur Rahman (14603354)

“…In this work, we investigated the effect of Nox2 loss of function on obesity-mediated alteration of bone remodeling using wild-type (WT) and Nox2-knockout (KO) mice fed with a standard lab chow diet (SD) as a control or a HFD as an obesity model. …”

Hemodynamics of small aneurysm pairs at the internal carotid artery by Jou, Liang-Der

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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

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COVID-19 and neuropathy in type 2 diabetes by Georgios Ponirakis (803076)

“…The long-COVID group exhibited significant changes in triglycerides and LDL (<i>P</i> < 0.05 for both) and body weight (<i>P</i> < 0.01) at follow-up. …”

Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser by Salem, Hayder

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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes by Noura Aldous (15429873)

Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype by Duaa W. Al-Sadeq (10976754)

“…</li><li>Circular Dichroism experiments suggested that the p.R336C mutation does not significantly alter the secondary structure of the CBS protein.…”

Metabolic signature of obesity-associated insulin resistance and type 2 diabetes by Haya Al-Sulaiti (5449256)

“…</p><h3>Results</h3><p dir="ltr">Our results showed that phospholipid metabolites including choline, glycerophosphoethanolamine and glycerophosphorylcholine were significantly altered from OIS when compared with OIR and T2DM individuals. …”

Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance by Zouhaier Farhani (22330693)

“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”

Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic by Mohamed Kayed Alhyasat, Khaled

“…Using the most advanced technological elements, this is a significant advancement in the automobile manufacturing sector. …”
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…In this study, we showed for the first time that arginine deprivation using a recombinant human arginase induces ferroptosis, an autophagy-mediated type of cell death in AML cells. Acute Myeloid Leukemia (AML) poses significant challenges due to its unfavorable prognosis and limited treatment options, particularly in elderly patients. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems by Local Burden of Disease HIV Collaborators (13279180)

The link between glycemic control measures and eye microvascular complications in a clinical cohort of type 2 diabetes with microRNA-223-3p signature by Sahar I. Da’as (9631717)

“…</p><h3>Results</h3><p dir="ltr">Over-expression of miR-223-3p alone was associated with significantly higher glucose (42.7 mg/dL, n = 75 vs 38.7 mg/dL, n = 75, p = 0.02) and degenerated retinal vasculature, and altered retinal morphology involving changes in the ganglion cell layer and inner and outer nuclear layers. …”

Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive Decline: A Cross-Sectional S... by Neyla S. Al-Akl (10914449)

“…Pathway analysis identified six significantly altered pathways, including arginine and unsaturated fatty acid biosynthesis, and the metabolism of the citrate cycle, alanine, aspartate, glutamate, a-linolenic acid, and glycerophospholipids. …”