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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
Published 2021“…On the other hand, the same study proved that the grid system and the villa model are the main reason behind the urban sprawl of the city. …”
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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
Published 2016“…Objective: The objectives of this study were to establish if R1 resection margin after esophagectomy was (i) a poor prognostic factor independent of patient and tumor characteristics, (ii) a marker of tumor aggressiveness and (iii) to look at the impact of adjuvant treatment in this subpopulation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan
Published 2022“…However, the impact of chronic infection on HRQoL remains unclear, while factors influencing the HRQoL may vary from one country to another. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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QNL and HERMES Project: Impact Stories
Published 2024“…<p dir="ltr">The presentation highlights the involvement of QNL’s ILDS section in the HERMES project and its significant impact on daily operations, users, and cost savings. …”
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The Impact of Implementing Maturity Models on IT Project Performance
Published 2021“…Recently, many models of maturity have emerged in IT sector, and there are few research studies on their benefits and impact on projects performance. The main aim is to study the impact of implementing project management maturity models on IT project performance. …”
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The impact of stakeholder integration on large-scale, innovative PPP infrastructure projects
Published 2020“…The thesis focused on single case study that helped to explore and define how to ensure stakeholders integration in innovative PPP projects. PPPs have received attention from researchers and practitioners for their effects and associated risks on projects and participating parties and the crucial role of the stakeholders in PPP projects that affect project outputs, outcomes, and impacts. …”
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Impact of COVID-19 on health-related quality of life (HRQOL) and functional status
Published 2024“…</p><h3>Conclusion</h3><p dir="ltr">Despite the impact of COVID-19 infection on quality of life, there was a significant improvement at 3 months. …”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…The staff pharmacists received training on how to address hyperkalemia when processing prescriptions. …”
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The ‘green’ start-up: environmental commitment and its impact on start-up success
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Impact of pharmacist-conducted anticoagulation patient education and telephone follow-up on transitions of care
Published 2021“…Background There is limited published data in Lebanon evaluating the impact of supplemental education for anticoagulants use, especially DOACs, on clinical outcomes such as bleeding. …”
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Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
Published 2025“…AB-FUBINACA treatment also causes a significant dose related decrease in sperm viability. …”