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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Mutation of the two residues in NLuc revealed a decreased but stable activity of the R162A, but not Q32A, mutant NLuc in live cell and in vitro assays performed using lysates prepared from cells expressing the proteins and with the furimazine substrate. …”
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Analyzing the use of e-textiles to improve application performance
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Machine Learning in the Analysis of Social Problems: The Case of Global Human Trafficking
Published 2019“…The Counter-Trafficking Data Collaborative (CTDC) dataset, which is an initiative of the International Organization for Migration (IOM) for human trafficking was used for the experimental study. The exploration of the dataset revealed 61% of missing data — another incentive for the applicability of machine learning via multiple imputation using chained equations (MICE) instead of single imputation or deletion. …”
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Use of smartphone and perception towards the usefulness and practicality of its medical applications among healthcare workers in Saudi Arabia
Published 2019“…Significance was considered at p-value of < 0.05. Results Utilization rate of smartphone was 42.3%, and only 6.1% of all healthcare providers reported always using applications in their practice. …”
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The use of multi-task learning in cybersecurity applications: a systematic literature review
Published 2024“…Five critical applications, such as network intrusion detection and malware detection, were identified, and several tasks used in these applications were observed. …”
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The Development And Significance Of Business Intelligence (BI) Platforms In Facilitating The Decision-Making Process In Dubai Government Entities
Published 2022“…Furthermore, the significance of using the BI platform for decision-making is established in the light of academic and empirical evidence. …”
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Enhancing Arabic Reading Proficiency as a Second Language: Unveiling the Significance of Audiobooks for Middle School Students
Published 2024“…Considering audiobooks as a useful tool in improving reading skills and language acquisition, this study aims to explore the potential benefits and effectiveness of using audiobooks as a tool for learning for non-Arab students in Dubai, as there is a diverse student population including individuals from various cultural and linguistic backgrounds which can present significant challenges. …”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
Published 2025“…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Chemosphere<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.chemosphere.2025.144735" target="_blank">https://dx.doi.org/10.1016/j.chemosphere.2025.144735</a></p>…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
