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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Predictors of diabetes fatalism among Arabs
Published 2018“…Age (β = −.14, 95% CI −.27, −.002), BMI (β = .35, 95% CI .15; .54), level of education (β = −3.98, 95% CI −7.64; −.32) and number of diabetes problems (β = −5.03, 95% CI −9.89; −.18) were significantly associated with diabetes fatalism in the regression model. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Body Shape Index Is a Stronger Predictor of Diabetes
Published 2019“…Nevertheless, the predictive level of ABSI for diabetes varied among different ethnicities. …”
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The predictors of successful methotrexate treatment of tubal ectopic pregnancy
Published 2024“…Age, pre-treatment β-hCG levels, sonographic presence of yolk sac, presence of foetal cardiac activity, and pelvic pain were significantly different between patients with successful and unsuccessful outcomes. …”
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Predictors of neurodevelopmental outcome for preterm infants with brain injury
Published 2009“…Multiple regression analyses distinguished the most significant predictors of mental and motor development. …”
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Predictors of Quality of Life and Glycemic Control among Saudi Adults with Diabetes
Published 2013“…Because of the chronic nature of diabetes, the goal of medical treatment and lifestyle modifications. is not only to prolong life but also to maintain a high level of QOL The aims of the present study are ; (i) to assess the QOL and glycemic control (GC) among diabetic patients at king Abdulaziz Medical City (KAMC), KSA, and (ii) to determine the significant predictors of QOL and GC.…”
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Incidence, predictors and severity of adverse events among whole blood donors
Published 2017“…Donor characteristics such as age, blood pressure, hemoglobin level, weight and history of donation were described and tested as potential risk predictors. …”
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Being an older refugees in Türkiye: predictors of mental health and quality of life
Published 2025“…The data were analyzed through ordinal and linear regression models, and significant predictors were identified.</p><h3 dir="ltr">Results</h3><p dir="ltr">Along with moderate stress levels, a significant proportion of participants were found to experience severe depression, affecting approximately 26.9% of the sample, as well as anxiety, which impacted 31.6%. …”
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Predictors of long-term survival after liver transplantation for hepatocellular carcinoma
Published 2005“…Encapsulation of the tumor and alpha-fetoprotein levels significantly affect patient survival. Five-year survival of patients with poorly differentiated (G3) HCC was significantly worse than that of patients with moderately (G2) or well-differentiated (G1) HCC (respectively, G3 44%, G2 67%, and G1 97%, p= 0.0015). …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Personality traits as predictors of vulnerability to persuasion in social engineering amongst risk-aware targets
Published 2025“…Participants were then asked about their level of trust in the potential social engineer and their likelihood of complying with the online request. …”
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The predictors of perforated appendicitis in the pediatric emergency department: A retrospective observational cohort study
Published 2021“…In the univariate analysis, male gender, vomiting, diarrhea, fever, elevated white blood cell count (WBC) levels, and high C-reactive protein (CRP) were identified as predictors of PA. …”
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The predictors of perforated appendicitis in the pediatric emergency department: A retrospective observational cohort study
Published 2021“…In the univariate analysis, male gender, vomiting, diarrhea, fever, elevated white blood cell count (WBC) levels, and high C-reactive protein (CRP) were identified as predictors of PA. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
