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An improved HIC using a new ordering and grouping algorithm
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Optimal Group Formation in Dense Wi-Fi Direct Networks for Content Distribution
Published 2019“…The results reveal significant performance gains in terms of group formation time and network throughput. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Predicting the Heats of Fusion of Ionic Liquids via Group Contribution Modeling and Machine Learning
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Undergraduate nursing students' perceptions of active learning strategies: A focus group study
Published 2023“…Data collected from the discussions were transcribed and thematically analyzed and aligned with the Taxonomy of Significant Learning. Results Study results show that undergraduate nursing students affirm that the use of active learning strategies supports the acquisition of foundational understanding, application and integration of knowledge, caring about the learning process, learning to learn, and the human dimension of learning. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Cellulose-based materials for antimicrobial water treatment: functionalization strategies and applications
Published 2025“…Water contamination by pathogenic microorganisms poses a significant threat to public health and ecosystems, necessitating the development of sustainable and efficient water decontamination technologies. …”
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Formal Verification of a Security Protocol in Vehicular Communication
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A critical overview of thin films coating technologies for energy applications
Published 2023“…Such techniques have their own significance to develop the energy efficiency devices. …”
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Application of Exopolymeric Substances and Biosurfactants in removal of heavy metals in Qatari soil and water
Published 2023“…<p dir="ltr">Heavy metals are economically important for industrial applications, but they are significant pollutants for the environment. …”
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A systematic review of Arabic text classification: areas, applications, and future directions
Published 2023“…This review also underscores the potential applications of ATC in addressing current challenges across various industries and highlights the significance of developing a benchmark dataset for ATC to facilitate model comparison. …”
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