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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
Published 2025“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”
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A Machine Learning Approach on Chest X-Rays for Pediatric Pneumonia Detection
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Palliative Tumor Control by Trabectedin in Pediatric Advanced Sarcoma
Published 2011“…The patient's quality of life improved as noted by a significant decrease in opiate requirements and ability to tolerate oral intake. …”
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
Published 2021“…The city of Sharjah is among the Gulf cities that have increased in size at an unprecedented rate by all standards, and within a period of time not exceeding four decades, after it remained confined within its old wall since its inception until the beginning of the seventies of the last century, with an area of 2.5 square kilometers. …”
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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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Nurses’ work environment and intent to leave in Lebanese hospitals
Published 2011“…Regression analysis revealed that for every 1 point score decrease on career development there was a 93% increase in likelihood of reporting intent to leave country. …”
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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury
Published 2021“…A mild form of TBI was induced in 11-week old male Sprague Dawley rats by weight drop. Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …”
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Social Media Use and Body Checking Among Lebanese Adults
Published 2022“…Participants (n = 423, 18-50 years old of both genders), filled a questionnaire measuring body checking, social media use, self-esteem, perceived stress and emotional eating. …”
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Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
Published 2024“…However, there was no significant impact on cardiovascular function and mitochondrial bioenergetics. …”
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
Published 2023“…Smoking was significantly more common among respondents who were older than 18 years old, married, held master's and PhD degrees, and working in non‐health‐related fields (<i>p</i> < 0.0001). …”
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Dissecting the signaling pathways regulating the vascular endothelial growth factor (VEGF) in brain tumor cells. (c2017)
Published 2017“…However, when both RhoA and RhoC were knocked down, VEGF expression decreased after EGF stimulation. Moreover, when the astrocytoma cells were subjected to hypoxia at different times, we detected a significant increase in pERK. …”
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Characterizing the dynamics of climate and native desert plants in Qatar
Published 2024“…Increased drought seasons correlated with changes in annual temperature, dew point, and soil temperature. Vegetation growth depended not only on rainfall amount but also on the number of rainfall events and accumulation. …”
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Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Our analysis reveals that the vocabulary has changed significantly and multiple spellings exist for several words. …”
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained?
Published 2025“…Fasting blood glucose decreased significantly across the five time points, from 9.27 ± 4.11preop to 7.06 ± 2.70 <sub>year9 </sub>mmol/L. …”
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The impact of maternal care on child development
Published 2019“…An increase of 6.5 h per week in the time 2-year-olds spend with their mothers significantly improves their non-cognitive skills.…”
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Initial risk assessment for pulmonary hypertension in patients with COPD
Published 2012“…Diffusion capacity was lower but did not reach statistical significance (P = 0.07). In multivariate analysis, statistically significant independent variables were >3% decrease in exercise oxyhemoglobin saturation and decline in prebronchodilator FEV1 (P = 0.01 and P = 0.04, respectively). …”
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A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar
Published 2023“…We found a significant decrease in the intake of vegetables, increases in the intake of soft drinks, fried food, fast food, and sweets, and a reduction in physical activity during schools’ closure compared to before. …”