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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
Published 2025“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
Published 2025“…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …”
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Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…Therefore, designing the urban block with a significant diversity in building heights, or gradual height variation will have the potential of a shading effect and wind speed increase to enhance the thermal performance of the urban block. …”
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The effect of building height diversity on outdoor microclimate conditions in hot climate. A case study of Dubai-UAE
Published 2020“…An urban configuration with significant variation in the buildings' height resulted in more reduction in outdoor air temperature compared to a config uration with gradual variation in the buildings' heights. …”
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Perceptions and Experiences of Female Police Officers Regarding Gender After 10 Years of Recruitment in the ISF: 2012-2022
Published 2023“…The ISF in Lebanon has seen a slow but gradual increase in the recruitment of women, with only two women recruited in 2001 and a significant increase to 800 women in 2012, after 11 years. …”
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …”
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The Impact of the 2019 Lebanese Multidimensional Crisis on Young Adults’ Political Attitudes and Behavior
Published 2022“…This crisis has led to an increase in political mistrust, alteration in political affiliations, and a gradual decrease in political interest.…”
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Can "Whatsapp" be the new luxury "app"? (c2018)
Published 2018“…As the luxury market reached saturation due to its gradual expansion and rapid customer growth, luxury brands felt compelled to embrace various social media platforms. …”
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Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers
Published 2015“…We then measure the effect of the gradual increase of FA concentration on the fluorescence intensity of Dox in phosphate-buffered saline (PBS) solutions (pH of 7.4). …”
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