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Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy .
Published 2020“…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …”
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Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation.
Published 2021“…Bubble flows caused significant cell injury. Preexposure to DEX or DHEA decreased cell death significantly. …”
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Wind energy potential along the onshore and offshore Qatar
Published 2020“…Wind energy is one among the clean and renewable energy resources. The utilization of non-conventional energies over the conventional sources helps to reduce the carbon emissions significantly. …”
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Selection of Bacillus spp. with decontamination potential on multiple Fusarium mycotoxins
Published 2021“…In vivo mycotoxin degradation potential of BM344-1 tested on artificially contaminated maize showed 25-44% reduction of ZEN and 15-19% reduction of T-2, with a non-significant effect in case of combined mycotoxins contamination. …”
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Allergenicity of roasted peanuts treated with a non-human digestive protease
Published 2015“…Results indicate that alcalase digestion of sonicated peanuts significantly increased protein solubility while decreasing Ara h 1 and Ara h 2 concentrations in both soluble and insoluble portions of peanuts relative to untreated peanuts. …”
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Investigation Into the Effects of Non-Linear Loading of Domestic Power Network on Home Appliances
Published 2016“…The effects of increasing non-linear loads in residential setting can be significant especially on single-phase motors connected to the same line. …”
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Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract
Published 2019“…Syzygium cumini (S. cumini) is an evergreen tropical plant that is well recognized for its therapeutic potential of common diseases. In this study, the therapeutic potential and biomedical application of S. cumini are assessed in vitro and in vivo to find its effectiveness for different complications. …”
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The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals
Published 2020“…Comparing supplementation responders and non-responders we found more pronounced changes in abundance of major phyla in responders, and a significant decrease in Bacteroides acidifaciens in non-responders. …”
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Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications
Published 2017“…Permselective properties of natural phenols were significantly improved at low polymerization potentials. …”
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Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress
Published 2015“…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. Pre-treatment of cells with piperine and its cyclohexylamino analog decreased the tunicamycin-induced upregulation of GRP78 and CHOP. …”
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Impact assessment of non-indigenous jellyfish species on the estuarine community dynamic: A model of medusa phase
Published 2017“…Low water discharge and low nutrient retention rate appear to be the most favourable conditions for B. virginica. The species is a non-selective predator able to integrate into the system effectively and has caused a decrease in the biomass of other organisms in the estuarine ecosystem throughout the summer after dam removal. …”
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Glucose and transferrin liganded PLGA nanoparticles internalization in non-small cell lung cancer cells
Published 2020“…Results: The results pointed to a significantly improved internalization rate of the liganded compared to PLGA NPs. …”
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Relationship between the heart rate and E/A ratio in athletic and non-athletic males in different ages
Published 2011“…Student t-test was used to establish the differences between transmitral and TDI determined velocities and indices in athletes and non-athletes. Results: The E/A decreased with age, the rate of decrease was slower in the physically trained subjects, except in children. …”
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Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
Published 2019“…In LPS-treated cells, pretreatments with silymarin-HSA noncomplex recovered the cell viability and decreased the ROS level and corresponding apoptosis more significantly than free silymarin. …”
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…As the drill pipe rotational speed increased, the pressure drop decreased slightly until a critical rotatory speed was reached, thereafter, the pressure drop increased markedly. …”
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